Milk Fever (Parturient Paresis) in Dairy Cows—A Review

Peripartal alterations of calcitonin gene‐related peptide and minerals in dairy cows affected by milk fever

“…It is characterized by a rapid decline of calcium (Ca) concentrations in plasma . This disease has been described for more than 2 centuries, with the first reports in the literature about MF dating back to 1793 . Different hypotheses have been generated over the years to explain the etiopathogenesis of MF; however, the underlying mechanisms of MF are not well understood.…”

“…Different hypotheses have been generated over the years to explain the etiopathogenesis of MF; however, the underlying mechanisms of MF are not well understood. The hypothesis that has gained most support to date is that MF is a perturbation of Ca homeostasis at or near parturition . Despite many advances made in prevention of MF, its incidence, as indicated by most recent epidemiologic studies, is relatively high.…”

“…1,2 This disease has been described for more than 2 centuries, with the first reports in the literature about MF dating back to 1793. 3 Different hypotheses have been generated over the years to explain the etiopathogenesis of MF 3,4 ; however, the underlying mechanisms of MF are not well understood. The hypothesis that has gained most support to date is that MF is a perturbation of Ca homeostasis at or near parturition.…”

“…The hypothesis that has gained most support to date is that MF is a perturbation of Ca homeostasis at or near parturition. [2][3][4][5] Despite many advances made in prevention of MF, 5 its incidence, as indicated by most recent epidemiologic studies, is relatively high. For example, it was shown that on a herd level, this condition affected between 4 and 8% of cattle in the USA, 5 between 4 and 9% in the UK, 4 and between 2 and 5% in Australia.…”

Determinação e avaliação de fatores que afetam a produtividade de vacas leiteiras: aspectos sanitários e reprodutivos.

“…Os tratamentos de Ca intravenosos (normalmente 8 a 10 g de Ca) produzem muito bons resultados e são capazes de manter a vaca viva até que os intestinos e ossos se adaptem aos mecanismos que transportam o Ca. Aproximadamente de 60 a 70% das vacas morrem dentro de um ou dois dias após a manifestação dos sintomas, quando não tratadas (Hibbs, 1950).…”