Miliary Tuberculosis Associated with Multiple Intracranial Tuberculomas

Serum Interleukin-2 and Neopterin Levels as Useful Markers for Treatment of Active Pulmonary Tuberculosis

“…In 2000, the World Health Organization (WHO) reported 8 million new tuberculosis cases and observed that 2.2 million people had lost their lives owing to this condition (World Health Organization 2000). Although tuberculosis is mainly affecting the lungs, extra pulmonary involvements have been published (Egeli et al 2003;Esme et al 2004;Ceylan and Gencer 2005). Therefore, a better understanding of the pathogenesis of this condition and the development of novel prevention and management strategies are necessary.…”

Intracranial Tuberculomas: An Unusual Cause of Altered Mental Status in a Pediatric Patient

“…Typically, early complaints are non-specific, like headache, loss of appetite, weight loss, and fever (as in our patient) (3,5). As these lesions gradually increase in size, signs and symptoms of increased intracranial pressure (i.e., nausea, vomiting, blurred vision), focal neurologic deficit, and seizure become more common presentations.…”

“…The clinical presentation of intracranial tuberculoma can vary from the asymptomatic, to the subtle, to the dramatic, depending on the time of presentation (3,9). Typically, early complaints are non-specific, like headache, loss of appetite, weight loss, and fever (as in our patient) (3,5).…”

“…They are usually formed by conglomeration of several miliary tubercules, which form around the outer sheaths of the small cerebral vessels (2). The clinical presentation of cerebral tuberculoma can vary from asymptomatic to fever, headache (and other signs of increased intracranial pressure), seizure (especially in children), cranial nerve palsies, and focal neurologic deficit (3)(4)(5)(6). Imaging with computed tomography (CT) or magnetic resonance imaging is highly sensitive for tuberculoma, but their specificity for definitive diagnosis is low (5,7).…”

Unusual Presentation of Tuberculosis as a Splenic Mass

“…Tuberculosis (TB) is an affective disease on different age groups ranging from children to elderly (Ceylan and Gencer 2005). TB is known to influence different systems of the human body; in particular its common abdominal sites are the ileocaecal region, mesenteric lymph nodes, and the peritoneum (Dawson 1995;Bozer et al 2001).…”