Milia en Plaque

Muñoz-Martínez, R.; Santamarina-Albertos, Alba; Sanz‐Muñoz, C.; Miranda‐Romero, A.

doi:10.1016/j.adengl.2012.07.033

Cited by 7 publications

(6 citation statements)

References 10 publications

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“…The primary form lacks a definite cause and usually regresses spontaneously. Moreover, secondary MEP has been linked to other conditions such as discoid lupus, pseudoxanthoma elasticum, amyloidosis, and even follicular hamartomas like trichoadenoma [1][2][3][4][5][6][7]. Conversely, secondary MEP has also been associated with radiotherapy, oral cyclosporine use, and certain dermatological procedures like dermabrasion and cryotherapy, as previously described by Beutler et al in this journal [7].…”

Section: Case Discussionmentioning

confidence: 89%

Milia en plaque on the shoulder as an early manifestations of mycosis fungoides

Rodrigues,

Cabral,

Alvim

et al. 2024

DOJ

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Section: Case Discussionmentioning

confidence: 89%

Milia en plaque on the shoulder as an early manifestations of mycosis fungoides

Rodrigues,

Cabral,

Alvim

et al. 2024

DOJ

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“…Multiple, clustered miliary cysts and larger infundibular cysts may occur in different settings [including LPFT, milia en plaque (MEP), CLE, and FMF, among the others (Table 1)] 10‐12 . MEP is a rare condition of unknown etiopathogenesis, whose clinical presentation is characterized by the presence of one or more plaques containing multiple grouped asymptomatic milia in a specific location 17,18 ; lesions may have a unilateral or bilateral distribution. MEP and LPFT have a similar distribution of lesions, leading some authors to speculate that the former may serve as a precursor to the latter; it seems more likely, however, that the cystic epithelial changes observed in LPFT are the consequence of the primary inflammatory aggression of the hair follicles, and not vice versa.…”

Section: Discussionmentioning

confidence: 99%

“…MEP and LPFT have a similar distribution of lesions, leading some authors to speculate that the former may serve as a precursor to the latter; it seems more likely, however, that the cystic epithelial changes observed in LPFT are the consequence of the primary inflammatory aggression of the hair follicles, and not vice versa. Histopathologically, MEP can be easily differentiated from LPFT because of the presence of only a mild‐to‐moderate, nonlichenoid chronic inflammatory infiltrate in the perifollicular dermis 1,17,18 …”

Section: Discussionmentioning

confidence: 99%

Lichen planus follicularis tumidus: Immunotyping of the inflammatory infiltrate with focus on plasmacytoid dendritic cells

Saggini

Kempf²,

Kutzner

2020

J Cutan Pathol

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Lichen planus follicularis tumidus (LPFT) is a rare clinicopathological variant of lichen planus (LP), clinically presenting with red-to-violaceous plaques studded with comedo-like lesions and keratin-filled milia-like cysts. Histopathologically, LPFT is characterized by cystically dilated follicular infundibula in the dermis, surrounded by a dense lichenoid lymphoid infiltrate with an associated interface reaction. We describe the clinicopathological features of an additional case of LPFT, focusing on the number and distribution of CD123(+) TCF4(+) plasmacytoid dendritic cells (pDCs). In our case, pDCs represented approximately 5% of the total inflammatory infiltrate, predominantly exhibiting a lichenoid distribution around the infundibula with no evidence of cluster formation, thus ruling out cutaneous lupus erythematosus. Our report is the first to describe the number and distribution of pDCs in LPFT. The results of our immunohistochemical analysis corroborate the notion that LPFT should be regarded as a rare variant of LP.

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“…The clinical differential diagnosis of milia en plaque is listed in Table 2 [18,19]. It includes not only local conditions, but also systemic disorders with skin lesions that may mimic milia en plaque.…”

Section: Discussionmentioning

confidence: 99%

Cryotherapy-induced milia en plaque: case report and literature review

Beutler

Cohen²

2015

Dermatology Online Journal

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Background: Cryotherapy-induced milia is a rarely described cutaneous reaction that may occur in patients who have received cryotherapy with liquid nitrogen. Cryotherapy-induced milia is characterized by 1-2 millimeter white dermal cysts that develop at the healed cryotherapy site. Milia en plaque, an erythematous plaque containing numerous milia, has not previously been described following treatment of a skin lesion with liquid nitrogen cryotherapy.Purpose: We describe a man who developed cryotherapy-induced milia en plaque after receiving cryotherapy to his dorsal hand for the treatment of an actinic keratosis. We also summarize the potential complications of cryotherapy, the differential diagnosis of milia en plaque, and therapeutic interventions for this lesion.Materials and methods: The features of a man with cryotherapy-induced milia en plaque are presented. Using PubMed, the following terms were searched and relevant citations assessed: cryosurgery, cryotherapy, hypothermia, milia and milia en plaque. In addition, the literature on cryotherapy-induced milia and cryotherapy-induced milia en plaque is reviewed.Results: Our patient developed cryotherapy-induced milia en plaque shortly after his cryotherapy site had healed. Some of the asymptomatic cystic dermal lesions had spontaneously resolved when a lesional biopsy was performed to confirm the diagnosis. The diagnosis, natural course, and potential treatments were discussed with the patient. Subsequent management was to observe the area; at follow-up examination, the remainder of the milia had also spontaneously resolved.Conclusion: Cryotherapy-induced milia is a benign condition characterized by the development of small white dermal cystic lesions that develop at a healed liquid nitrogen cryotherapy site. The lesions may appear individually or as milia en plaque. Although the mechanism of pathogenesis is unknown, it may represent a variant of traumatic milia. The diagnosis of milia en plaque can usually be established by clinical presentation. If necessary, a biopsy can be performed to provide pathologic confirmation of the suspected diagnosis. Treatment options include manual extraction, topical retinoids, or observation. As was seen in our patient, the milia may resolve spontaneously.

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Milia en Plaque

Cited by 7 publications

References 10 publications

Milia en plaque on the shoulder as an early manifestations of mycosis fungoides

Milia en plaque on the shoulder as an early manifestations of mycosis fungoides

Lichen planus follicularis tumidus: Immunotyping of the inflammatory infiltrate with focus on plasmacytoid dendritic cells

Cryotherapy-induced milia en plaque: case report and literature review

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