Mild cognitive impairment: some steps forward

Mateos, Raimundo

doi:10.1017/s1041610218001886

Cited by 2 publications

(1 citation statement)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A survey developed among expert neurologists showed that 90% of them recognize MCI as a clinical diagnostic entity 12 . In WoS, MCI yields more than 650 reviews and 37 books 13 …”

Section: Methods and Main Bibliographic Findingsmentioning

confidence: 99%

Predementia constructs: Mild cognitive impairment or mild neurocognitive disorder? A narrative review

Bermejo‐Pareja

Contador

Ser

et al. 2020

Int J Geriat Psychiatry

View full text Add to dashboard Cite

Background: Predementia is a heuristic umbrella concept to classify older adults with cognitive impairment who do not suffer dementia. Many diagnostic entities have been proposed to address this concept, but most of them have not had widespread acceptance. Aims: To review clinical definitions, epidemiologic data (prevalence, incidence) and rate of conversion to dementia of the main predementia constructs, with special interest in the two most frequently used: mild cognitive impairment (MCI) and minor neurocognitive disorder (miNCD). Methods: We have selected in three databases (MEDLINE, Web of Science and Google scholar) the references from inception to 31 December 2019 of relevant reviews, population and community-based surveys, and clinical series with >500 participants and >3 years follow-up as the best source of evidence. Main results: The history of predementia constructs shows that MCI is the most referred entity. It is widely recognized as a clinical syndrome harbinger of dementia of several etiologies, mainly MCI due to Alzheimer's disease. The operational definition of MCI has shortcomings: vagueness of its requirement of "preserved independence in functional abilities" and others. The recent miNCD construct presents analogous difficulties. Current data indicate that it is a stricter predementia condition, with lower prevalence than MCI, less sensitivity to cognitive decline and, possibly, higher conversion rate to dementia. Conclusions: MCI is a widely employed research and clinical entity. Preliminary data indicate that the clinical use of miNCD instead of MCI requires more scientific evidence. Both approaches have common limitations that need to be addressed.

show abstract

“…A survey developed among expert neurologists showed that 90% of them recognize MCI as a clinical diagnostic entity 12 . In WoS, MCI yields more than 650 reviews and 37 books 13 …”

Section: Methods and Main Bibliographic Findingsmentioning

confidence: 99%

Predementia constructs: Mild cognitive impairment or mild neurocognitive disorder? A narrative review

Bermejo‐Pareja

Contador

Ser

et al. 2020

Int J Geriat Psychiatry

View full text Add to dashboard Cite

show abstract

Risk of mild cognitive impairment among older adults in the United States by ethnoracial group

Perales‐Puchalt

Gauthreaux

Shaw

et al. 2020

Int. Psychogeriatr.

View full text Add to dashboard Cite

Objectives: To compare the risk of mild cognitive impairment (MCI) among a wide range of ethnoracial groups in the US. Design: Non-probabilistic longitudinal clinical research. Setting: Participants enrolling into the National Alzheimer’s Coordinating Center Unified Data Set recruited via multiple approaches including clinician referral, self-referral by patients or family members, or active recruitment through community organizations. Participants: Cognitively normal individuals 55 and older at the initial visit, who reported race and ethnicity information, with at least two visits between September 2005 and November 2018. Measurements: Ethnoracial information was self-reported and grouped into non-Latino Whites, Asian Americans, Native Americans, African Americans (AAs), and individuals simultaneously identifying as AAs and another minority race (AA+), as well as Latinos of Caribbean, Mexican, and Central/South American origin. MCI was evaluated clinically following standard criteria. Four competing risk analysis models were used to calculate MCI risk adjusting for risk of death, including an unadjusted model, and models adjusting for non-modifiable and modifiable risk factors. Results: After controlling for sex and age at initial visit, subhazard ratios of MCI were statistically higher than non-Latino Whites among Native Americans (1.73), Caribbean Latinos (1.80), and Central/South American Latinos (1.55). Subhazard ratios were higher among AA+ compared to non-Latino Whites only in the model controlling for all risk factors (1.40). Conclusion: Compared to non-Latino Whites, MCI risk was higher among Caribbean and South/Central American Latinos as well as Native Americans and AA+. The factors explaining the differential MCI risk among ethnoracial groups are not clear and warrant future research.

show abstract

Mild cognitive impairment: some steps forward

Cited by 2 publications

References 14 publications

Predementia constructs: Mild cognitive impairment or mild neurocognitive disorder? A narrative review

Predementia constructs: Mild cognitive impairment or mild neurocognitive disorder? A narrative review

Risk of mild cognitive impairment among older adults in the United States by ethnoracial group

Contact Info

Product

Resources

About