Mild cognitive impairment among rural‐dwelling older adults in China: A community‐based study

Liu, Cong; Ren, Yifei; Wang, Yongxiang; Hou, Tingting; Dong, Yi; Han, Xiaobin; Yin, Ling; Zhang, Qinghua; Feng, Jianli; Wang, Lidan; Tang, Shi; Grande, Giulia; Laukka, Erika J.; Du, Yifeng; Qiu, Chengxuan

doi:10.1002/alz.12629

Cited by 50 publications

(67 citation statements)

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“…The prevalence of MCI in rural areas has been reported to be as high as over 26% [ 24 ], making its study in the rural context relevant and the investigation of the factors that may be associated with cognitive decline in those areas important. This review aimed to summarize the latest research on the differences between rural- and urban-dwelling older adults with MCI.…”

Section: Discussionmentioning

confidence: 99%

Mild Cognitive Impairment in Rural Areas: Research Advances and Implications for Clinical Practice and Healthcare Policy

et al. 2022

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Mild cognitive or neurocognitive impairment (MCI) may be more prevalent in rural areas. Differences between rural and urban MCI patients in terms of risk factors, course and prognosis are rarely reported. The present review aims to summarize the latest research on MCI in rural areas. A literature search was performed in the databases of PubMed, Scopus and ScienceDirect for articles published over the last decade. Eleven articles were included in this review, reporting on the differences between rural and urban MCI patients. Several risk factors, such as older age, lack of activities and food insecurity have been associated with MCI in both rural and urban areas, whereas others, such as obesity, adverse childhood experiences and plasma chemokine C-C motif ligand 11 (considered as a potential negative regulator of neurogenesis), differed according to the place of residence. No specific protective factor for rural women has been reported. There is some evidence that MCI may present earlier in rural residents, but that progression to dementia may be more rapid in urban residents. It seems that there may be clinically relevant differences in the onset, course and prognosis of MCI with regards to the place of residence (urban vs rural). Those differences should be taken into account for the design of health policies and service delivery across different settings.

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Section: Discussionmentioning

confidence: 99%

Mild Cognitive Impairment in Rural Areas: Research Advances and Implications for Clinical Practice and Healthcare Policy

et al. 2022

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“…This population-based cross-sectional study used data collected from participants in the baseline examination of the Multimodal Interventions to Delay Dementia and Disability in rural China (MIND-China) in Yanlou Town, Yanggu County in Shandong Province, conducted by Shandong Provincial Hospital in collaboration with the Yanlou Town Health Center. As a participating project in the World-Wide FINGERS Network (a global network for dementia risk reduction and prevention) [16], MIND-CHINA was aimed to test the effects of multidomain interventions (e.g., lifestyle and nutritional guidelines, physical exercise, cognitive training, and improvement in the management of major cardiovascular risk factors) on cognitive decline and onset of dementia and disability among rural-dwelling elderly people [17]. MIND-China targeted older adults who were aged 60 years or older and living in the 52 communities (villages) in Yanlou Town.…”

Section: Study Design and Participantsmentioning

confidence: 99%

Red cell distribution width, anemia, and lower-extremity physical function among rural-dwelling older adults

et al. 2022

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Background Elevated red cell distribution width (RDW) has been associated with degenerative conditions in aging. Aims We aimed to evaluate the associations of RDW and anemia with lower-extremity physical function among rural-dwelling older adults. Methods This population-based cross-sectional study included 5093 rural residents (age ≥ 60 years, 57.3% women) who participated in the MIND-China Study in Shandong. Data were collected via face-to-face interviews, clinical examinations, and laboratory tests. RDW was categorized according to quartiles and the lower-extremity physical function was assessed using the Short Physical Performance Battery (SPPB), Results Multiple linear regression analyses suggested that the fourth quartile of RDW (vs. first quartile) was associated with lower SPPB summary score (β-coefficient – 0.38; 95% CI – 0.58 to – 0.18) and lower scores in balance test (– 0.09; – 0.17 to – 0.01), chair stand test (– 0.17; – 0.27 to – 0.07), and walking speed test (– 0.12; – 0.19 to − 0.05). Anemia was associated with a multiple-adjusted β-coefficient of – 0.34 (– 0.52 to – 0.16) for SPPB summary score. Stratified analysis by anemia showed that there was a linear association between RDW and SPPB in individuals without anemia but a J-shaped association in individuals with anemia. Discussion This large-scale population-based study revealed the associations of high RDW and anemia with poor lower-extremity physical function among rural-dwelling Chinese older adults. These findings suggest that an elevated RDW might be a biochemical marker for poor lower-extremity physical function among older adults. Conclusions Anemia and an elevated RDW are associated with poor performance in lower-extremity physical function among rural-dwelling Chinese older adults.

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“…China has a low prevalence of knowledge of dementia, which is viewed as a normal part of the aging process, and the behavioral and cognitive symptoms of dementia are attributed to mental illnesses ( Liu et al, 2008 ). A recent study showed that more than a quarter of the rural elderly in China is at a high risk of dementia ( Cong et al, 2022 ). However, dementia has not yet received enough attention at the national level in China, and a national strategic action plan for dementia has not been considered in the “Healthy China 2030” Plan and China’s Medium- and Long-term Plan for the Prevention and Treatment of Chronic Diseases (2017–2025) ( Wang et al, 2022 ).…”

Section: Introductionmentioning

confidence: 99%

Senile dementia and psychiatric stigma among community health service providers and relatives of diagnosed and suspected dementia patients: a cross-sectional study

Zhang

Deng

Luo

et al. 2023

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Background The number of people suffering from dementia is increasing rapidly in China. Early identification, referral, and intervention for dementia patients within communities are important to public health. However, these measures could be impacted by misconceptions about dementia and associated psychiatric stigma from community health professionals and relatives of dementia patients. Methods A cross-sectional survey was conducted on 249 participants, which included community doctors, community nurses, and relatives of diagnosed and suspected dementia patients in Guiyang, China. Participants were recruited through convenient sampling. The Chinese version of Dementia Knowledge Assessment Scale (DKAS) and the Perceived Psychiatric Stigma Scale (PPSS) were used to evaluate the participants’ knowledge of dementia and dementia-related psychiatric stigma. Results A total of 249 participants completed the questionnaire. The participants had moderate overall knowledge of dementia and the associated psychiatric stigma. Participants who were ≥45 years old, had a low level of education, had a low monthly income, or gained knowledge of dementia through non-media channels had lower awareness of dementia and stronger psychiatric stigma. In the “Communication & behavior” subscale of DKAS, all participants had a low level of awareness. Relatives of diagnosed and suspected dementia patients had higher total PPSS and “Marital preclusion” subscale scores than community doctors and nurses but lower psychiatric stigma based on the PPSS “Self-deprecation” subscale score. Conclusions Despite their profession, community doctors and nurses did not show an absolute advantage over relatives of diagnosed and suspected dementia patients in the dementia knowledge, and they even showed higher psychiatric stigma in some subscales. The self-deprecation subscale is related to the identification with negative labels such as “people with a mental illness are the weak”. This study shows that reducing stigma on the “Self-deprecation” subscale should be a core component of training and educational programs targeted at improving dementia knowledge among community health service providers.

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Mild cognitive impairment among rural‐dwelling older adults in China: A community‐based study

Cited by 50 publications

References 53 publications

Mild Cognitive Impairment in Rural Areas: Research Advances and Implications for Clinical Practice and Healthcare Policy

Mild Cognitive Impairment in Rural Areas: Research Advances and Implications for Clinical Practice and Healthcare Policy

Red cell distribution width, anemia, and lower-extremity physical function among rural-dwelling older adults

Senile dementia and psychiatric stigma among community health service providers and relatives of diagnosed and suspected dementia patients: a cross-sectional study

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