Mild Carbohydrate Intolerance in Pregnancy

Abstract

Diagnosis of Gestational Diabetes Mellitus (GDM) requires at least two or more values to be abnormal on the 3 h-100 g oral glucose tolerance test: but how to care for pregnant women with only one abnormal glucose value remains a point of discussion. In fact, although a large number of studies on this argument exist, the clinical significance of "one abnormal value" has yet to be clarified. Our review of previous studies and personal experience on prevalence, metabolic findings and maternal-fetal outcome suggests this pregnancy induced carbohydrate intolerance is a continuum with GDM, associated with an increased incidence of materno-fetal complications. For this reason we believe that it should be diagnosed, monitored and treated.

Retrospective evaluation of perinatal outcome in women with mild gestational hyperglycemia

“…Diagnosis of GDM requires at least two or more values to be abnormal on the 3 h 100‐g oral glucose tolerance test (OGTT), but how to care for pregnant women with a lesser degree of hyperglycemia remains a point of discussion. There are many studies on this argument, but the clinical significance of MGH has yet to be clarified 3 . MGH defines glucose intolerance in pregnancy as characterized by a positive 50‐g glucose challenge test (GCT) and/or a single abnormal value on antepartum OGTT that has not met the criteria for a diagnosis of GDM 4 …”