Mild and Highly Efficient Protocol for the Synthesis of Benzimidazoles Using Samarium Triflate [Sm(OTf)₃]

p‐Dodecylbenzenesulfonic Acid: An Efficient Brønsted Acid‐Surfactant‐Combined Catalyst to Carry out Diverse Organic Transformations in Aqueous Medium

“…2‐substituted benzimidazole moiety is very common in many commercially available drug molecules such as Esomeprazole, Albendazole, Astemizole etc tungstate promoted zirconia, Sm(OTf) 3 , nano‐MnFe 2 O 4 , etc were employed for the synthesis of 2‐substituted benzimidazoles ( 34 ) starting from aromatic aldehydes ( 8 ) and o‐phenylenediamines ( 33 ) in absence or presence of various organic solvents such as methanol, acetonitrile, 1,4‐dioxane etc . In 2013, Kumar et al .…”

Samarium(III) Triflate as an Efficient and Reusable Catalyst for the Facile Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles

“…Our group has also been working on developing Lewis acid-based, greener approaches for synthesizing different types of heterocyclic compounds [47][48][49]. One of the popular catalyst metal triflates has widely been employed in cyclocondensation and other organic reactions [50][51][52][53][54][55][56][57][58][59][60]. The main reasons are again lying in its fantastic features such as water-tolerant nature, high selectivity, and its reusability.…”

Molecularly Engineering Defective Basal Planes in Molybdenum Sulfide for the Direct Synthesis of Benzimidazoles by Reductive Coupling of Dinitroarenes with Aldehydes

“…In general, the most common methodologies for the synthesis of 2-subtituted benzimidazoles rely on using o -phenylenediamines as starting materials. The traditional synthesis involves the reaction of these reagents with carboxylic acid derivatives under strongly acidic conditions, sometimes at high temperature or under microwave irradiation. − Another conventional method makes use of aldehydes, which led to the formation of the Schiff’s bases by condensation reaction with o -phenylenediamines, followed by cyclization and aerobic oxidation of the C–N bond to form the target compounds. − In addition, the metal-catalyzed oxidative or acceptorless dehydrogenative − coupling of primary alcohols with o -phenylenediamines have also been proposed as effective synthetic methods for the preparation of benzimidazoles.…”