This study tested whether there was a relationship between migration, unemployment, and urbanization based on the Harris-Todaro model in 12 regions of Turkey, which were formed according to NUTS-1 classification, in the period between 2008 and 2019. For this purpose, panel data methods that consider cross-section dependency were used in the study. As a result of the analysis, it was concluded that the Harris-Todaro model was valid in TR1, TR2, TR3, TR4, TR5, and TR6 regions. In TR7, TR8, TR9, TRA, TRB, and TRC regions, it was found that the Harris-Todaro model was not valid.