1997
DOI: 10.1006/biol.1997.0082
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Migration: Public Health Issues (Polio, Hepatitis A, Hepatitis B, Tuberculosis, Diphtheria)

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“…Many of these subjects (about 50%) presented normal ALT and undetectable serum HBV DNA in PCR. The data about the normal ALT levels is not surprising, because many studies have evidenced as, particularly in sub-Saharan African population, HBV-infection is characterized by an elevated prevalence (>8%), but many infected subjects (a variable rate of 40%-65% in the different studies) not present biochemical activity of diseases (10,14,15) . The high rate of HBs-positive patients with undetectable DNA in PCR is probably connected with the use of primers not adequate for some HBV isolates from Africa.…”
Section: Discussionmentioning
confidence: 98%
“…Many of these subjects (about 50%) presented normal ALT and undetectable serum HBV DNA in PCR. The data about the normal ALT levels is not surprising, because many studies have evidenced as, particularly in sub-Saharan African population, HBV-infection is characterized by an elevated prevalence (>8%), but many infected subjects (a variable rate of 40%-65% in the different studies) not present biochemical activity of diseases (10,14,15) . The high rate of HBs-positive patients with undetectable DNA in PCR is probably connected with the use of primers not adequate for some HBV isolates from Africa.…”
Section: Discussionmentioning
confidence: 98%
“…All of these subjects presented elevated serum ALT levels and detectable serum HBV-DNA in PCR. The data about the elevated ALT levels is surprising, because many studies have evidenced that in immigrant subjects, particularly in sub-Saharan African population, but also in South American people, HBV infection is characterized by an elevated prevalence (> 8%), but many infected subjects (a variable rate of 40-65% in the different studies) not present biochemical activity of diseases [11,14,15]. Probably, our data is connected with the low number of infected subjects.…”
Section: Discussionmentioning
confidence: 54%
“…Some recent studies have evidenced that in immigrants the prevalent infectious diseases are represented by HIV, tuberculosis and chronic viral hepatitis, more frequently caused by HBV [11][12][13][14][15]. People coming from South America represent about 20% of total immigrants in Italy and they are an important community in our country.…”
Section: Discussionmentioning
confidence: 99%