PURPOSE
Over 80% of US patients initiate HD with a tunneled dialysis catheter (TDC). Published data on TDC outcomes are based on a case-mix of prevalent and incident TDCs. We analyzed factors affecting patency and complications of first TDCs ever placed in a large cohort of incident HD patients.
MATERIALS AND METHODS
We retrospectively queried a prospective, computerized vascular access database to identify 472 patients receiving a first ever TDC. Multiple variable survival analysis was used to identify clinical parameters affecting TDC patency (from placement to non-elective removal) and infection (from placement to first episode of catheter-related bacteremia).
RESULTS
The median patency of all TDCs was 202 days. Left-sided placement of TDCs was the only variable associated with inferior TDC patency (hazard ratio 1.98; 95% CI, 1.39–2.81, p<0.0001). The 6-month TDC patency was 37% for left interval jugular (LIJ) vein catheters vs 54% for right internal jugular (RIJ) vein catheters. The one-year patency was 6% for LIJ catheters vs 35% for RIJ catheters. Catheter patency was not associated with patient age, sex, race, hypertension, diabetes, coronary artery disease, peripheral vascular disease, cerebrovascular disease, or heart failure. The median time to the first episode of catheter-related bacteremia was 163 days. None of the clinical variables was associated with TDC infection.
CONCLUSIONS
TDCs are plagued by high rates of infection. Right IJ vein TDC should be used preferentially to maximize catheter patency.