Migration and potential risk of trace phthalates in bottled water: A global situation

Luo, Qiong; Liu, Zehua; Yin, Hua; Dang, Zhi; Wu, Pingxiao; Zhu, Nengwu; Zhang, Lin; Liu, Yu

doi:10.1016/j.watres.2018.10.002

Cited by 146 publications

(49 citation statements)

References 88 publications

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“…Lou’s study revealed also the phthalates-associated potential risks in both human daily intake and estrogenic effect. According to the authors despite drinking bottle water posed low health concern, the adverse estrogenic effects of phthalates in bottled water from some countries appeared to be significant [ 215 ].…”

Section: Occurrence Of Paes In Foodmentioning

confidence: 99%

Critical Review on the Presence of Phthalates in Food and Evidence of Their Biological Impact

Giuliani

Zuccarini

Cichelli

et al. 2020

IJERPH

196

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Phthalates are a huge class of chemicals with a wide spectrum of industrial uses, from the manufacture of plastics to food contact applications, children’s toys, and medical devices. People and animals can be exposed through different routes (i.e., ingestion, inhalation, dermal, or iatrogenic exposure), as these compounds can be easily released from plastics to water, food, soil, air, making them ubiquitous environmental contaminants. In the last decades, phthalates and their metabolites have proven to be of concern, particularly in products for pregnant women or children. Moreover, many authors reported high concentrations of phthalates in soft drinks, mineral waters, wine, oil, ready-to-eat meals, and other products, as a possible consequence of their accumulation along the food production chain and their accidental release from packaging materials. However, due to their different physical and chemical properties, phthalates do not have the same human and environmental impacts and their association to several human diseases is still under debate. In this review we provide an overview of phthalate toxicity, pointing out the health and legal issues related to their occurrence in several types of food and beverage.

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Section: Occurrence Of Paes In Foodmentioning

confidence: 99%

Critical Review on the Presence of Phthalates in Food and Evidence of Their Biological Impact

Giuliani

Zuccarini

Cichelli

et al. 2020

IJERPH

196

View full text Add to dashboard Cite

show abstract

“…Drinks (PET plastics, cans or glass), hot or cold and natural or traditional, may be canned, bottled or packaged. Drinking crops, drinking processing and drink packing are innovative features in the drinking sector that are catalyzed by the demands for nonalcoholic beverages (Luo et al, 2018). The beverage industry is very large, involving a lot of products; as a result, it pollutes the atmosphere and environment.…”

Section: Beverage Industrymentioning

confidence: 99%

Waste Polyethylene Terephthalate Packaging Materials in Developing countries – Sources, Adverse Effects, and Management

Elehinafe¹,

Kolawole²,

Beture³

et al. 2021

Ecol. Eng. Environ. Technol.

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“…With the definition of estrogenic potency, it is convenient to identify which are strong EDCs, while which are weak. The potential adverse effect of each EDC depends on both its estrogenic potency and concentration, thus the concept of estrogen equivalence (EEQ) has been widely adopted (Luo et al, 2018;.. This above criterion well describes the potential adverse effect of one individual EDC at any given concentration.…”

Section: Significance Of This Workmentioning

confidence: 99%

“…However, many EDCs cannot be well explained with the above conception. For example, di-2-(ethyl hexyl) phthalate, well-known as DEHP, the estrogenic potency of which was as low as 10 -7 , suggesting an extremely weak EDC (Luo et al, 2018). Considering its possible human exposure level to normal population, DEHP as an EDC unlikely pose potential adverse effects to human.…”

Section: Significance Of This Workmentioning

confidence: 99%

Are Hydrogen Peroxide, Hypochlorite and Peracetic Acid Potential Endocrine Disruptors?

Zhong¹,

Zhang²,

Z³

et al. 2020

Preprint

Self Cite

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Arylsulfatase and β-glucuronidase are two important enzymes in human, which play important role on dynamic equilibrium of steroidal estrogens. This work probably for the first time reported that hydrogen peroxide (H2O2), hypochlorite and peracetic acid (PAA) could effectively inhibit the activities of arylsulfatase and/or β-glucuronidase. The 50 percent of inhibitions (IC50) of H2O2, and PAA on arylsulfatase were found to be 142.90±9.00, 91.83±10.01, and 43.46±2.92 μM, respectively. The corresponding respective IC50 of hypochlorite and PAA on β-glucuronidase were 704.90±41.40 and 23.26±0.82 μM, while H2O2 showed no inhibition on β-glucuronidase. It was further revealed that the inhibition of hypochlorite on both arylsulfatase and β-glucuronidase was irreversible. On the contrary, the inhibition by H2O2 and PAA was reversible. Moreover, it was found that the inhibitions of arylsulfatase and/or β-glucuronidase by these three chemicals were pH-dependent, among which the inhibition by H2O2 was competitive and non-competitive for PAA. In general, H2O2 and hypochlorite can be endogenously produced in human, which suggested that the two compounds are potential endocrine disruption compounds (EDCs) as they can cause endocrine disruption via inhibition of arylsulfatase and β-glucuronidase. This work further indicated that any agent that can induce production of H2O2 or hypochlorite in human is potential EDC, which explains why some EDCs with very weak or no estrogenic potency can cause endocrine disruption that confirmed in epidemiological studies.

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Migration and potential risk of trace phthalates in bottled water: A global situation

Cited by 146 publications

References 88 publications

Critical Review on the Presence of Phthalates in Food and Evidence of Their Biological Impact

Critical Review on the Presence of Phthalates in Food and Evidence of Their Biological Impact

Waste Polyethylene Terephthalate Packaging Materials in Developing countries – Sources, Adverse Effects, and Management

Are Hydrogen Peroxide, Hypochlorite and Peracetic Acid Potential Endocrine Disruptors?

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