Migration and asthma medication in international adoptees and immigrant families in Sweden

Bråbäck, Lennart; Vogt, Hartmut; Hjern, Anders

doi:10.1111/j.1365-2222.2011.03744.x

Cited by 33 publications

(32 citation statements)

References 37 publications

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“…Prior studies have found similar associations in Mexican Americans (12)(13)(14)(15)34) and, recently, in nonHispanic whites and African Americans (15). Similar findings have been reported for immigrants to Great Britain, Sweden, and, more variably, Israel (35)(36)(37).…”

Section: Discussionsupporting

confidence: 70%

Pulmonary Disease and Age at Immigration among Hispanics. Results from the Hispanic Community Health Study/Study of Latinos

Barr

Avilés-Santa

Davis

et al. 2016

Am J Respir Crit Care Med

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Section: Discussionsupporting

confidence: 70%

Pulmonary Disease and Age at Immigration among Hispanics. Results from the Hispanic Community Health Study/Study of Latinos

Barr

Avilés-Santa

Davis

et al. 2016

Am J Respir Crit Care Med

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“…It is most likely that the lower prevalence of allergy seen in children from hand dishwashing families is related to lifestyle factors, but lifestyle factors other than dishwashing practices may be important. For example, overcrowded housing, 20 low socioeconomic status, 28,29 and immigration status 30 are all factors that have been associated with reduced allergy levels in various studies, and these factors may also be associated with dishwashing practices. We used multivariate OPLS analyses to screen the data for confounders and covariates, but despite adjusting for such factors in logistic regression models, the associations between hand dishwashing and allergy, and traditional cooking and allergy, remained, implying that a causal relationship might be possible.…”

Section: Figurementioning

confidence: 99%

Allergy in Children in Hand Versus Machine Dishwashing

2015

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BACKGROUND AND OBJECTIVE: The hygiene hypothesis stipulates that microbial exposure during early life induces immunologic tolerance via immune stimulation, and hence reduces the risk of allergy development. Several common lifestyle factors and household practices, such as dishwashing methods, may increase microbial exposure. The aim of this study was to investigate if such lifestyle factors are associated with allergy prevalence.METHODS: Questionnaire-based study of 1029 children aged 7 to 8 years from Kiruna, in the north of Sweden, and Mölndal, in the Gothenburg area on the southwest coast of Sweden. Questions on asthma, eczema, and rhinoconjunctivitis were taken from the International Study of Asthma and Allergies in Childhood questionnaire. RESULTS:Hand dishwashing was associated with a reduced risk of allergic disease development (multivariate analysis, odds ratio 0.57; 95% confidence interval: 0.37-0.85). The risk was further reduced in a dose-response pattern if the children were also served fermented food and if the family bought food directly from farms. CONCLUSIONS:In families who use hand dishwashing, allergic diseases in children are less common than in children from families who use machine dishwashing. We speculate that a less-efficient dishwashing method may induce tolerance via increased microbial exposure. WHAT'S KNOWN ON THIS SUBJECT:Microbial exposure during early life may prevent, or reduce, the risk of allergy development. WHAT THIS STUDY ADDS:Allergic diseases are less common in children whose parents use hand dishwashing instead of machine dishwashing, and we hypothesize that this allergy-preventive effect is mediated via an increased microbial exposure. Dr Hesselmar has been involved in the planning and design of the study, the design of the protocols used, the writing of the manuscript, the data/statistical analyses, and in the interpretation of the results; Dr Hicke-Roberts has been involved in the planning and design of the study, in the design of the protocols used, data collection and data handling, and in the writing of the manuscript and the interpretation of the results; and Dr Wennergren has been involved in the writing of the manuscript and the interpretation of the results. The hygiene hypothesis stipulates that microbial exposure during early life induces immunologic tolerance via immune stimulation, and hence reduces the risk of allergy development. In this epidemiologic study, we wanted to explore daily-life exposure patterns, presumed to affect microbial exposure, to test if these exposure patterns are associated with less allergy development in children. We postulated that there is an allergy-preventing effect associated with dishwashing practices and dietary habits; lifestyle factors that, if proven, could be used in allergy prevention in affluent countries. METHODSIn September 2007, a questionnaire was sent to the parents/guardians of all children aged 7 to 8 years resident in Kiruna or Mölndal. Kiruna is a town in the north of Sweden; Mölndal is an integrated p...

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“…Adolescent immigrants from Ethiopia and the former Soviet Union to Israel also had a significantly lower prevalence of asthma compared to children born in Israel of the same ethnicity [23]. A Swedish study using inhaled corticosteroid prescriptions as a surrogate indicator of asthma prevalence found that these prescriptions were higher in Swedish-born children of foreign-born parents (adjusted OR 3.36, 95% CI 3.10–3.66) compared to foreign-born children who had migrated to Sweden after birth with their biological parents [22]. …”

Section: Second-generation International Immigrantsmentioning

confidence: 99%

“…The prevalence of reported hay fever (31 vs. 19%, RR 1.6, 95% CI 1.4–1.9), asthma (9 vs. 3.6%, RR 2.5, 95% CI 1.7–3.8), and eczema (4.9 vs. 2.1%, RR 2.1, 95% CI 1.2–3.7) was higher in the boys who arrived in Sweden before 2 years of age compared to those who arrived between 2 and 6 years of age. The prevalence of purchased prescribed inhaled corticosteroids obtained from the Swedish Prescribed Drug Register, used as a surrogate indicator of asthma prevalence, also decreased with older age at the time of migration in both internationally adopted children and foreign-born children of foreign-born immigrant parents who had migrated to Sweden [22]. …”

Section: First-generation International Immigrantsmentioning

confidence: 99%

Effects of Migration on Allergic Diseases

Tham

Zhu

2018

Int Arch Allergy Immunol

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Studies in migrant populations provide vital opportunities to investigate the role of environmental factors in the pathogenesis of allergic disorders. Differences in allergy prevalence have been observed between migrants and native-born subjects living in the same geographical location. Immigrants who migrate from less affluent countries with lower allergy prevalence tend to have a lower prevalence of allergic disorders compared to native-born residents of the more affluent host country. The patterns of allergic disease prevalence also differ between first- and second-generation migrants. The timing of migration in relation to birth, age at migration, and duration of residence in the host country also influence one’s atopic risk. A complex interplay of multiple environmental, socioeconomic, and cultural factors is likely responsible for these observed differences. Further research into the roles of various risk factors in modulating differences in allergic disease prevalence between migrant and native populations will enhance our understanding of the complex gene-environment interactions involved in the pathogenesis of allergic disorders.

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Migration and asthma medication in international adoptees and immigrant families in Sweden

Cited by 33 publications

References 37 publications

Pulmonary Disease and Age at Immigration among Hispanics. Results from the Hispanic Community Health Study/Study of Latinos

Pulmonary Disease and Age at Immigration among Hispanics. Results from the Hispanic Community Health Study/Study of Latinos

Allergy in Children in Hand Versus Machine Dishwashing

Effects of Migration on Allergic Diseases

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