“…Propagation of CSD is totally independent of the vascular reaction: cortical, hippocampal, cerebellar and retinal nervous tissue support CSD perfectly well in vitro (BureS et al, 1974;Martins-Ferreira, 1984;Do Carmo, 1992). Therefore, it is questionable whether or not CSD sets up a cycle of potassium-induced vasoconstriction of importance for its propagation (Young and Van Vliet, 1992). During return to normal of ionic changes, rCBF increases by ~ 100% in anaesthetized animals (Leao, 1944ft;Lauritzen, 1987a), simultaneously with the release of lactate to the brain interstitial fluid (Scheller et al, 1992).…”