Migraine-like headache and ocular malformations may herald Moyamoya syndrome

Verdure, P.; Moigne, O. Le; Massardier, Evelyne; Vanhulle, Catherine; Tollard, É.; Maltête, David

doi:10.1016/j.neurol.2011.09.011

Cited by 5 publications

(4 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[1] Early diagnosis and initiation of therapy may have the potential to improve patient survival, especially in metastatic tumors. [11] In our report, the patient survived for 8 months after diagnosis through supportive therapies associated with radio and chemotherapy.…”

Section: Discussionmentioning

confidence: 64%

“…[9] Anatomopathological diagnosis is made by the presence of a brown pigmented lesion in the leptomeninges. [11] Immunohistochemical study shows a positive reaction to anti-melanoma antibodies (HMB-45), Protein S-100 and vimentin. [12] Early diagnosis is important and gives the possibility to initiate the more appropriated treatment modality.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Primary Diffuse Meningeal Melanomatosis – Case Report

Fagundes,

Arleu,

Do Rosário

2023

Rev. Foco

View full text Add to dashboard Cite

Background: The diffuse meningeal melanomatosis (MM) is part of a group of rare melanocytic diseases. Aiming to emphasize aspects of the natural history, diagnosis and treatment of this rare disease we decide to report the present case. Cade Description: A 17 years-old girl presenting with headache for the last 45 days, followed by episodes of agitation and hallucinations. CT scan revealed mild meningeal enhancement on the right hemisphere. MRi revealed significant diffuse dura--mater thickening, invading cerebral cortex and white matter, including the brain stem. The study of cerebrospinal fluid showed the presence of neoplastic cells, cytology confirmed melanocytes. The histological study, carried out from the brain biopsy, showed diffuse melanocytes infiltrating the meninges, at the subarachnoid space and cerebral cortex. The histological diagnosis was diffuse MM. Conclusions: In conclusion, diffuse MM is a rare condition of malignant characteristics and usually has a poor prognosis. Early diagnosis is essential to determine and expand the patient's therapy.

show abstract

Section: Discussionmentioning

confidence: 64%

Section: Discussionmentioning

confidence: 99%

Primary Diffuse Meningeal Melanomatosis – Case Report

Fagundes,

Arleu,

Do Rosário

2023

Rev. Foco

View full text Add to dashboard Cite

show abstract

“…Other uncommon ocular findings in MMD patients are referred to in this section from 12 articles, including optic nerve involvement, congenital cataract, and retinochoroidal anomaly ( Table 2) (34,38,(42)(43)(44)(45)(46)(47)(48)(49)(50)(51). In Case 31, a 13-year-old female patient was diagnosed with congenital glaucoma and MMD.…”

Section: Other Ocular Findingsmentioning

confidence: 99%

Moyamoya Disease Associated With Morning Glory Disc Anomaly and Other Ophthalmic Findings: A Mini-Review

et al. 2020

View full text Add to dashboard Cite

Moyamoya disease (MMD) is a chronic cerebrovascular disease that frequently results in intracranial ischemia or hemorrhage. Its concurrence with varying ophthalmic findings is relatively rare yet may lead to irreversible blindness. We performed a search and review of the literature to characterize the relevance of MMD (excluding moyamoya syndrome) and ophthalmic findings. As a result, a total of 38 articles identified from PubMed and Web of Science were included in this mini-review. Patients with MMD sometimes present with decreased visual acuity or visual field defects before the onset of symptomatic cerebrovascular dysfunction. The most predominant ophthalmic condition in MMD patients is the morning glory disc anomaly (MGDA). Deficiency during neuroectodermal genesis and subsequent mesodermal changes may be responsible for the association between these two diseases. Thus, it may be beneficial for patients with MGDA to receive cerebral vascular examinations as the precaution against life-threatening intracranial angiopathy. Other ophthalmic findings reported in cases of MMD include retinal vascular occlusion, optic disc pallor, cortical blindness, etc. For most of the patients with MMD, retinal examinations would be recommended to prevent potential loss of vision. It is essential for both neurologists and ophthalmologists to be aware of the correlation between cerebrovascular diseases such as MMD and ocular manifestations to achieve a comprehensive diagnosis.

show abstract

“…This includes refraction errors (myopia, astigmatism, hyperopia), heterotropia (strabismus), inflammatory disease (keratitis, uveitis, scleritis), infections (corneal ulcers, conjunctivitis, endophthalmitis), and glaucoma (closed-angle, neovascular), as well as orbital pathologies (cellulitis, orbital pseudotumors, tendinitis), and any affection of the fifth cranial pair. [21][22][23][24][25][26] Among children, the leading cause of headaches are migraine and tension-type headache, [27][28][29] though they are considered to be fairly rare, occurring in 2-5% of those below the age of 15 years, with the peak incidence occurring between the ages of 10 and 15. 30 Approximately 4.3% of the children and adolescents experience headaches by the age of two or three, with a gradual increase until they reach school age.…”

Section: Introductionmentioning

confidence: 99%

Pediatric patients at a high risk of headache of ocular origin: the HAMS Score (Hyperopia, Astigmatism, Myopia, and Strabismus)

Siqueira

Andrade-Valença

Andrade

et al. 2021

View full text Add to dashboard Cite

Pediatric patients identified at increased risk for headache due to ocular refractive errors were evaluated to produce a diagnostic tool called the HAMS score that will help establish the likelihood of headache due to refractive errors.Methods Data on the ocular diagnosis and headache complaints of 726 pediatric patients of both sexes were obtained from the medical records of an ophthalmological service in Brazil (Hospital de Olhos Santa Luzia). Age, use of glasses, and ocular diagnosis were also considered to create an index based on the number of ocular diagnoses in a given individual (HAMS score) to verify their association with the incidence of headache. Once the database was finalized, it was then analyzed to identify the variables capable of predicting the occurrence of headaches, following which a profile of those at the highest risk was produced by comparison.Results Only the ocular diagnosis was significantly associated with headache as a function of sex, age, use of glasses, farsightedness, astigmatism, myopia, and strabismus, indicating the relative impact of each ocular diagnosis on the probability of headache. According to the HAMS score, strabismus is more likely to have headache (5.21), followed by hyperopia (3.10), myopia (2.67), and, finally, astigmatism (1.86). The findings showed that the presence or absence of refraction errors and strabismus is predictive of the occurrence of headache, particularly in a small group of patients (6.2%) where the probability of headache was 57.8%. Such patients were characterized by being younger, having a combination of strabismus, hyperopia, and astigmatism, and already be using corrective lenses.Conclusion The index based on the most common ocular diagnoses (HAMS score) is effective, and it has practical application in identifying children and adolescent patients with a greater or lesser propensity for headaches of ophthalmic origin.

show abstract

Migraine-like headache and ocular malformations may herald Moyamoya syndrome

Cited by 5 publications

References 6 publications

Primary Diffuse Meningeal Melanomatosis – Case Report

Primary Diffuse Meningeal Melanomatosis – Case Report

Moyamoya Disease Associated With Morning Glory Disc Anomaly and Other Ophthalmic Findings: A Mini-Review

Pediatric patients at a high risk of headache of ocular origin: the HAMS Score (Hyperopia, Astigmatism, Myopia, and Strabismus)

Contact Info

Product

Resources

About