Migraine Disability Awareness Campaign in Asia: Migraine Assessment for Prophylaxis

Wang, Shuu Jiun; Chung, Chin-Sang; Chankrachang, Siwaporn; Ravishankar, K.; Merican, Julia Shahnaz; Salazar, Gerard; Siow, Charles; Cheung, Raymond T.F.; Phanthumchinda, Kammant; Sakai, Fumihiko

doi:10.1111/j.1526-4610.2008.01088.x

Cited by 35 publications

(37 citation statements)

References 17 publications

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“…In a study performed in Turkey [1], a total of 66.4% of all patients reported headache in neurology outpatient clinics and 36.8% of patients with headache were diagnosed as migraine according to International Headache Society (IHS) criteria. Our finding suggested that the prevalence of migraine among neurological headache outpatients in China is somewhat lower than that in other Asian countries [6]. The discrepancy may attribute to the different study methodology, genetic and socio-cultural factors in different countries.…”

Section: Discussioncontrasting

confidence: 56%

“…Approximately 19.5% of all neurological outpatients complained of headache and the prevalence of migraine was 23.8% among headache patients. A multinational cross-sectional study conducted in 8 Asian countries indicated that migraineurs comprised the majority of patients who consulted their neurologists with headache complaints, the proportion ranging from 50.9% to 85.8% across different countries [6]. In a study performed in Turkey [1], a total of 66.4% of all patients reported headache in neurology outpatient clinics and 36.8% of patients with headache were diagnosed as migraine according to International Headache Society (IHS) criteria.…”

Section: Discussionmentioning

confidence: 99%

“…Despite its high prevalence and proven disability for the patients, migraine remains underdiagnosed and undertreated in clinical performance, even in neurology practice [4,5]. A study conducted in 8 Asian countries disclosed that only 58.6% of migraineurs had received a physician diagnosis of migraine before the study, and many patients did not benefit from their current migraine management [6]. Furthermore, many unrecognized migraineurs are lacking of effective treatments and then consult their physicians for headache frequently.…”

Section: Introductionmentioning

confidence: 99%

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Diagnosis and treatment status of migraine: A clinic-based study in China

Li¹,

Zhou²,

Tan³

et al. 2012

Journal of the Neurological Sciences

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Section: Discussioncontrasting

confidence: 56%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Diagnosis and treatment status of migraine: A clinic-based study in China

Li¹,

Zhou²,

Tan³

et al. 2012

Journal of the Neurological Sciences

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“…In a clinical study from a headache center in east Hungary [4], migraine was the most common headache, while TTH patients reported more severe disability than migraines. A study from Asia [5] also showed that migraine was the most common headache diagnosis in neurological services. A population survey in Chile [6] indicated that migraineurs were more likely to consult doctors than TTH patients.…”

Section: Introductionmentioning

confidence: 99%

Classification and clinical features of headache patients: an outpatient clinic study from China

et al. 2011

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This study aimed to analyze and classify the clinical features of headache in neurological outpatients. A cross-sectional study was conducted consecutively from March to May 2010 for headache among general neurological outpatients attending the First Affiliated Hospital of Chongqing Medical University. Personal interviews were carried out and a questionnaire was used to collect medical records. Diagnosis of headache was according to the International classification of headache disorders, 2nd edition (ICHD-II). Headache patients accounted for 19.5% of the general neurology clinic outpatients. A total of 843 (50.1%) patients were defined as having primary headache, 454 (27%) secondary headache, and 386 (23%) headache not otherwise specified (headache NOS). For primary headache, 401 (23.8%) had migraine, 399 (23.7%) tension-type headache (TTH), 8 (0.5%) cluster headache and 35 (2.1%) other headache types. Overall, migraine patients suffered (1) more severe headache intensity, (2) longer than 6 years of headache history and (3) more common analgesic medications use than TTH ones (p < 0.001).TTH patients had more frequent episodes of headaches than migraine patients, and typically headache frequency exceeded 15 days/month (p < 0.001); 22.8% of primary headache patients were defined as chronic daily headache. Almost 20% of outpatient visits to the general neurology department were of headache patients, predominantly primary headache of migraine and TTH. In outpatient headaches, more attention should be given to headache intensity and duration of headache history for migraine patients, while more attention to headache frequency should be given for the TTH ones.

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“…[1][2][3] Migraine was ranked as the seventh-highest specific cause of disability and the third most prevalent disorder worldwide in Global Burden of Disease Survey 2010, with a prevalence of 6.5% in men and 18.2% in women. [4][5][6] however, it still remains under-reported, under-diagnosed and under-treated. Highest prevalence is found in age groups 25 to 55 years.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of propranolol, flunarizine and divalproex sodium in prophylaxis of migraine

Bhat

Sidhu

Goyal³

2017

Int J Basic Clin Pharmacol

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Background: Preventive treatment has an important role in the management of migraine. Propranolol and flunarizine have been used for more than two decades while, open-label, controlled studies suggest divalproex sodium may also be efficacious for migraine prevention. The objective of the study to compare efficacy and safety of propranolol, flunarizine and divalproex sodium in patients for migraine prophylaxis.Methods: Following approval from IEC a 12-week randomized, open, comparative study was carried out at the outpatient department of Medicine. Patients between 18 to 65 years, with history of 3 to 12 migraines a month (IHS) for six months were included. Patients were divided into three groups of 30 patients to receive - propranolol 20 to 160mg/day; flunarizine 5 to 10mg/day or divalproex sodium 250 to 750mg/day, for three months.Results: Total 90/116 patients completed the study. No significant differences were found between the groups with regards to mean age or other baseline migraine features. All the drugs significantly decreased the frequency, duration and severity of migraine (P<0.001). There is no statistically significant difference between propranolol, flunarizine and divalproex sodium for any of the efficacy parameters. All the three treatments were well-tolerated and safe.Conclusions: All the three study drugs were equally effective with an acceptable tolerability profile, Divalproex sodium group showed more side effects, none of which were serious. However, further studies with larger number of patients and longer duration of treatment are recommended.

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Migraine Disability Awareness Campaign in Asia: Migraine Assessment for Prophylaxis

Cited by 35 publications

References 17 publications

Diagnosis and treatment status of migraine: A clinic-based study in China

Diagnosis and treatment status of migraine: A clinic-based study in China

Classification and clinical features of headache patients: an outpatient clinic study from China

Evaluation of propranolol, flunarizine and divalproex sodium in prophylaxis of migraine

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