Midterm Outcomes of Bridge-to-Recovery Patients After Short-Term Mechanical Circulatory Support

Cheng, Yi-Tso; Garan, A.R.; Sanchez, J.; Kurlansky, Paul; Ando, Masahiko; Cevasco, Marisa; Yuzefpolskaya, M.; Colombo, P.C.; Naka, Yoshifumi; Takayama, Hiroaki; Takeda, Koji

doi:10.1016/j.athoracsur.2019.01.060

Cited by 6 publications

(8 citation statements)

References 24 publications

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“…The use of VA-ECMO has increased substantially over the past several years, 2,3 but the rate of cardiac recovery observed remains low. 4,5 Left ventricular assist devices (LVADs) provide longterm mechanical circulatory support and also profoundly mechanically unload the left ventricle. 6 Multiple clinical studies have documented cardiac recovery using LVAD therapy, with a rate between 10% and 60% in selected populations.…”

Section: See Commentaries On Pages 401 and 403mentioning

confidence: 99%

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Proposal for a trial of early left ventricular venting during venoarterial extracorporeal membrane oxygenation for cardiogenic shock

et al. 2021

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Objective: Patients with profound cardiogenic shock may require venoarterial (VA) extracorporeal membrane oxygenation (ECMO) for circulatory support most commonly via the femoral vessels. The rate of cardiac recovery in this population remains low, possibly because peripheral VA-ECMO increases ventricular afterload. Whether direct ventricular unloading in peripheral VA-ECMO enhances cardiac recovery is unknown, but is being more frequently utilized. A randomized trial is warranted to evaluate the clinical effectiveness of percutaneous left ventricle venting to enhance cardiac recovery in the setting of VA-ECMO.Methods: We describe the rationale, design, and initial testing of a randomized controlled trial of VA-ECMO with and without percutaneous left ventricle venting using a percutaneous micro-axial ventricular assist device.Results: This is an ongoing prospective randomized controlled trial in adult patients with primary cardiac failure presenting in cardiogenic shock requiring peripheral VA-ECMO, designed to test the safety and effectiveness of percutaneous left ventricle venting in improving the rate of cardiac recovery. Conclusions:The results of this nonindustry-sponsored trial will provide critical information on whether left ventricle unloading in peripheral VA-ECMO is safe and effective. (JTCVS Open 2021;8:393-400) Schematic of the REVERSE Randomized Controlled Study.

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Section: See Commentaries On Pages 401 and 403mentioning

confidence: 99%

“…The use of VA-ECMO has increased substantially over the past several years, 2 , 3 but the rate of cardiac recovery observed remains low. 4 , 5 …”

mentioning

confidence: 99%

Proposal for a trial of early left ventricular venting during venoarterial extracorporeal membrane oxygenation for cardiogenic shock

et al. 2021

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“…VA-ECMO supports circulation while treatment of the underlying pathology is prioritized to facilitate successful weaning or bridge to HRT. Because the potential for ventricular recovery is often difficult to ascertain, we advocate that all patients where HRT is a realistic consideration undergo early evaluation even if the intended goal is recovery [2][3][4][5].…”

Section: Considerations Prior To Weaningmentioning

confidence: 99%

How I approach weaning from venoarterial ECMO

et al. 2020

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“…Em pacientes com choque cardiogênico secundário a IAM submetidos a ECMO VA o tempo médio de assistência circulatória varia de 5,1 dias a 7 dias 15,50. A médio prazo, o prognóstico desses pacientes depende de diversas variáveis. Cheng et al 51 , após seguimento de médio de 306 dias, demonstraram que, entre os pacientes que usaram dispositivo de curta permanência por choque cardiogênico de diversas etiologias, os que mais frequentemente precisavam de substituição cardíaca (transplante cardíaco ou dispositivo de assistência ventricular de longa permanência) foram os pacientes cuja etiologia do choque cardiogênico era isquêmica (p = 0,003).…”

Section: Recuperação E Plasticidade Do Músculo Cardíacounclassified

“…Entretanto, dos 149 pacientes que tiveram alta após desmame de ECMO VA secundária a choque cardiogênico, apenas 24,2% (n = 36) destes tinham choque cardiogênico após infarto 51 .…”

Section: Recuperação E Plasticidade Do Músculo Cardíacounclassified

Preditores de recuperação em pacientes com choque cardiogênico secundário a infarto agudo do miocárdio tratados com oxigenação por membrana extracorpórea

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Midterm Outcomes of Bridge-to-Recovery Patients After Short-Term Mechanical Circulatory Support

Cited by 6 publications

References 24 publications

Proposal for a trial of early left ventricular venting during venoarterial extracorporeal membrane oxygenation for cardiogenic shock

Proposal for a trial of early left ventricular venting during venoarterial extracorporeal membrane oxygenation for cardiogenic shock

How I approach weaning from venoarterial ECMO

Preditores de recuperação em pacientes com choque cardiogênico secundário a infarto agudo do miocárdio tratados com oxigenação por membrana extracorpórea

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