Middle East respiratory syndrome coronavirus on inanimate surfaces: A risk for health care transmission

Khan, Raymond; Al‐Dorzi, Hasan M.; Johani, Sameera Al; Balkhy, Hanan H.; Alenazi, Thamer H.; Baharoon, Salim; Arabi, Yaseen M.

doi:10.1016/j.ajic.2016.05.006

Cited by 16 publications

(10 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…SARS-CoV-2 has been demonstrated to survive on surfaces, such as plastic and steel, for up to 3 days 8 . This extensive spreading and prolonged survival opens the possibility of indirect transmission of SARS-CoV-2 from surfaces, which is consistent with data from prior coronavirus outbreaks such as Severe Acute Respiratory Syndrome (SARS) and Middle Easters Respiratory Syndrome (MERS) [9][10][11][12] . Infection clusters of SARS-CoV-2 have been reported, where no direct contact with an infected individual has occurred, but several persons in became infected 13,14 .…”

supporting

confidence: 85%

Disinfection effect of pulsed xenon ultraviolet irradiation on SARS-CoV-2 and implications for environmental risk of COVID-19 transmission

Simmons

Carrión

Alfson

et al. 2020

Preprint

View full text Add to dashboard Cite

Prolonged survival of SARS-CoV-2 on environmental surfaces and personal protective equipment (PPE) may lead to these surfaces transmitting disease to others. This article reports the effectiveness of a pulsed xenon ultraviolet (PX-UV) disinfection system in reducing the load of SARS-CoV-2 on hard surfaces and N95 respirators. Chamber slides and N95 respirator material were directly inoculated with SARS-CoV-2 and exposed to different durations of PX-UV disinfection. For hard surfaces, disinfection for 1, 2, and 5 minutes resulted in 3.53 Log10, >4.54 Log10, and >4.12 Log10 reductions in viral load, respectively. For N95 respirators, disinfection for 5 minutes resulted in >4.79 Log10 reduction in viral load. We found that PX-UV significantly reduces SARS-CoV-2 on hard surfaces and N95 respirators. With the potential to rapidly disinfectant environmental surfaces and N95 respirators, PX-UV devices are a promising technology for the reduction of environmental and PPE bioburden and to enhance both HCW and patient safety by reducing the risk of exposure to SARS-CoV-2.

show abstract

supporting

confidence: 85%

Disinfection effect of pulsed xenon ultraviolet irradiation on SARS-CoV-2 and implications for environmental risk of COVID-19 transmission

Simmons

Carrión

Alfson

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…& Human adenoviruses (HAdV) were detected from 63 of 141 (45%) fomite samples in an adult intensive care unit (ICU) in a hospital in Rio de Janeiro, Brazil, with viral loads ranging from 2.48 × 10 1 to 2.1 × 10 3 genomic copies per milliliter [69]. & Middle East respiratory syndrome coronavirus (MERS-CoV) was detected on 2 of 51 (4%) high-touch surfaces in patient rooms with laboratory-confirmed MERS-CoV patients [70].…”

Section: Presence and Abundancementioning

confidence: 99%

Microbial Exchange via Fomites and Implications for Human Health

et al. 2019

View full text Add to dashboard Cite

Purpose of Review Fomites are inanimate objects that become colonized with microbes and serve as potential intermediaries for transmission to/from humans. This review summarizes recent literature on fomite contamination and microbial survival in the built environment, transmission between fomites and humans, and implications for human health. Recent Findings Applications of molecular sequencing techniques to analyze microbial samples have increased our understanding of the microbial diversity that exists in the built environment. This growing body of research has established that microbial communities on surfaces include substantial diversity, with considerable dynamics. While many microbial taxa likely die or lay dormant, some organisms survive, including those that are potentially beneficial, benign, or pathogenic. Surface characteristics also influence microbial survival and rates of transfer to and from humans. Recent research has combined experimental data, mechanistic modeling, and epidemiological approaches to shed light on the likely contributors to microbial exchange between fomites and humans and their contributions to adverse (and even potentially beneficial) human health outcomes. Summary In addition to concerns for fomite transmission of potential pathogens, new analytical tools have uncovered other microbial matters that can be transmitted indirectly via fomites, including entire microbial communities and antibiotic-resistant bacteria. Mathematical models and epidemiological approaches can provide insight on human health implications. However, both are subject to limitations associated with study design, and there is a need to better understand appropriate input model parameters. Fomites remain an important mechanism of transmission of many microbes, along with direct contact and short-and long-range aerosols.

show abstract

“…Interestingly some studies reported the presence of the virus on surfaces (patient rooms) following discharge or death, which highlights the importance of strict and proper infection control practice in healthcare facilities [11]. …”

Section: Discussionmentioning

confidence: 99%

First Confirmed Case of Middle East Respiratory Syndrome Coronavirus Infection in the Kingdom of Bahrain: In a Saudi Gentleman after Cardiac Bypass Surgery

Seddiq

Al-Qahtani

Al‐Tawfiq

et al. 2017

Case Reports in Infectious Diseases

View full text Add to dashboard Cite

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is well known to cause severe respiratory infection and was first reported in the Kingdom of Saudi Arabia in 2012. We report here the first confirmed MERS-CoV infection in the Kingdom of Bahrain in a Saudi gentleman who was admitted electively for coronary bypass surgery, postoperatively developed an acute respiratory illness, and tested positive for MERS-CoV. 40 close contacts, all healthcare workers, were traced and followed with no documented secondary cases.

show abstract

Middle East respiratory syndrome coronavirus on inanimate surfaces: A risk for health care transmission

Cited by 16 publications

References 10 publications

Disinfection effect of pulsed xenon ultraviolet irradiation on SARS-CoV-2 and implications for environmental risk of COVID-19 transmission

Disinfection effect of pulsed xenon ultraviolet irradiation on SARS-CoV-2 and implications for environmental risk of COVID-19 transmission

Microbial Exchange via Fomites and Implications for Human Health

First Confirmed Case of Middle East Respiratory Syndrome Coronavirus Infection in the Kingdom of Bahrain: In a Saudi Gentleman after Cardiac Bypass Surgery

Contact Info

Product

Resources

About