Middle Ear Fluid Streptococcus pneumoniae Serotype Distribution in Costa Rican Children with Otitis Media

Arguedas, Adriano; Dagan, Ron; Guevara, Silvia; Porat, Nurith; Soley, Carolina; Pérez, Alexandra; Brilla, Roberto

doi:10.1097/01.inf.0000168748.92510.45

Cited by 27 publications

(25 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Other reported serotypes were, 3 (8%) [29,33,35], 18C (7%) [33,40], 1 (5%) [29,33], others (49%) [33,35,40], along with 6A [33], 4 [33] and 15C [33] (the most common forest plot in Fig. 3).…”

Section: Pneumococcal Serotypesmentioning

confidence: 94%

“…(19%) [33,40], 19A (17%) [35,40], 5 (15%) [29], 9V (11%) [33,40], 14 (9%) [29,33,35], and 23F (8%) [29,33,40] accounting for 60-70% of the strains isolated from AOM in the age group 3-86 months. Other reported serotypes were, 3 (8%) [29,33,35], 18C (7%) [33,40], 1 (5%) [29,33], others (49%) [33,35,40], along with 6A [33], 4 [33] and 15C [33] (the most common forest plot in Fig.…”

Section: Pneumococcal Serotypesmentioning

confidence: 98%

“…Thirteen studies [29,30,[32][33][34][35][36][37][38][39][40][41][42] provided information on middle ear effusion collected and cultured to document the bacteria responsible for AOM used in the meta-analysis on AOM etiology and four of these studies [29,33,35,40] provided information on specific AOM pneumococcal serotypes. Characteristics of these studies are presented in Table 1 and details of each study in Supplementary data.…”

Section: Etiologymentioning

confidence: 99%

See 2 more Smart Citations

Epidemiology of acute otitis media in children of Latin America and the Caribbean: A systematic review and meta-analysis

Bardach

Ciapponi

García-Martí

et al. 2011

International Journal of Pediatric Otorhinolaryngology

View full text Add to dashboard Cite

Section: Pneumococcal Serotypesmentioning

confidence: 94%

Section: Pneumococcal Serotypesmentioning

confidence: 98%

Section: Etiologymentioning

confidence: 99%

See 1 more Smart Citation

Epidemiology of acute otitis media in children of Latin America and the Caribbean: A systematic review and meta-analysis

Bardach

Ciapponi

García-Martí

et al. 2011

International Journal of Pediatric Otorhinolaryngology

View full text Add to dashboard Cite

“…The latter entailed removing and cleaning the ear canal by deep aspiration of the MEF material through the perforation to minimize contamination and spurious results. For the purposes of this study, only S. pneumoniae , NTHi, S. pyogenes and M. catarrhalis were considered true pathogens [26]. …”

Section: Methodsmentioning

confidence: 99%

Non-typeable Haemophilus influenzae and Streptococcus pneumoniaeas primary causes of acute otitis media in colombian children: a prospective study

Sierra¹,

López²,

Zapata³

et al. 2011

BMC Infect Dis

View full text Add to dashboard Cite

BackgroundAcute otitis media (AOM) is one of the most frequently encountered bacterial infections in children aged < 5 years; Streptococcus pneumoniae (S. pneumoniae) and non-typeable Haemophilus influenzae (NTHi) are historically identified as primary AOM causes. Nevertheless, recent data on bacterial pathogens causing AOM in Latin America are limited. This prospective study aimed to identify and characterize bacterial etiology and serotypes of AOM cases including antimicrobial susceptibility in < 5 year old Colombian children.MethodsFrom February 2008 to January 2009, children ≥3 months and < 5 years of age presenting with AOM and for whom a middle ear fluid (MEF) sample was available were enrolled in two medical centers in Cali, Colombia. MEF samples were collected either by tympanocentesis procedure or spontaneous otorrhea swab sampling. Bacteria were identified using standard laboratory methods, and antimicrobial resistance testing was performed based on the 2009 Clinical and Laboratory Standards Institute (CLSI) criteria. Most of the cases included in the study were sporadic in nature.ResultsOf the 106 enrolled children, 99 were included in the analysis. Bacteria were cultured from 62/99 (63%) of samples with S. pneumoniae, H. influenzae, or S. pyogenes. The most commonly isolated bacteria were H. influenzae in 31/99 (31%) and S. pneumoniae in 30/99 (30%) of samples. The majority of H. influenzae episodes were NTHi (27/31; 87%). 19F was the most frequently isolated pneumococcal serotype (10/30; 33%). Of the 30 S. pneumoniae positive samples, 8/30 (27%) were resistant to tetracycline, 5/30 (17%) to erythromycin and 8/30 (27%) had intermediate resistance to penicillin. All H. influenzae isolates tested were negative to beta-lactamase.ConclusionsNTHi and S. pneumoniae are the leading causes of AOM in Colombian children. A pneumococcal conjugate vaccine that prevents both pathogens could be useful in maximizing protection against AOM.

show abstract

“…[4][5][6][7] Pneumococcal diseases are more common in children younger than 2 years, elderly people, and in certain groups of individuals that present conditions associated with the development of invasive pneumococcal diseases (IPD) ( Table 2). [1][2][3][4][5][6][7][8][9][10][11][12] Moreover, they affect poorer populations more seriously, aggravating the situation of these populations even further. 1,4 In Brazil, the highest rate of incidence of pneumococcal meningitis has been registered in nursing infants younger than 1 year, and bacterial resistance has increased progressively.…”

Section: Introductionmentioning

confidence: 99%

Impacto da vacina conjugada contra Streptococcus pneumoniae em doenças invasivas

Bricks¹,

Berezin²

2006

J. Pediatr. (Rio J.)

View full text Add to dashboard Cite

. Articles retrieved with the keywords Streptococcus pneumoniae, pneumococcal diseases, conjugate vaccine, antimicrobial resistance and meningitis were reviewed. Summary of the findings:The introduction of heptavalent pneumococcal conjugate vaccine caused a dramatic reduction in the incidence of invasive pneumococcal diseases in American children, reduced antibiotic use and the number of medical visits due to otitis media and pneumonia by children. The incidence of invasive pneumococcal diseases caused by resistant strains declined in immunized children, adults and elderly individuals. In Brazil, the mortality rate of pneumococcal meningitis is very high and the resistance to antibiotics has increased over the last 5 years.Conclusions: Heptavalent pneumococcal conjugate vaccine can benefit not only children, but the entire community and should be included in the Brazilian routine immunization schedule.J Pediatr (Rio J). 2006;82(3 Suppl):S67-74: Streptococcus pneumoniae, pneumococcal disease, conjugate vaccines, pneumonia, meningitis, antimicrobial resistance.

show abstract

Middle Ear Fluid Streptococcus pneumoniae Serotype Distribution in Costa Rican Children with Otitis Media

Abstract: The serotype distribution of S. pneumoniae causing pediatric OM in Costa Rica is similar to those reported from developed countries. The current heptavalent pneumococcal conjugate vaccine covers 74% of OM episodes in Costa Rican children.

Cited by 27 publications

References 19 publications

Epidemiology of acute otitis media in children of Latin America and the Caribbean: A systematic review and meta-analysis

Epidemiology of acute otitis media in children of Latin America and the Caribbean: A systematic review and meta-analysis

Non-typeable Haemophilus influenzae and Streptococcus pneumoniaeas primary causes of acute otitis media in colombian children: a prospective study

Impacto da vacina conjugada contra Streptococcus pneumoniae em doenças invasivas

Contact Info

Product

Resources

About