Middle-ear disease in children with cleft palate

Karanth, Tulasi Kota; Whittemore, Kenneth R.

doi:10.1016/j.anl.2018.04.012

Cited by 13 publications

(12 citation statements)

References 99 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Sixteen percent to 32% of infants with CP may experience feeding challenges beginning at birth that can last throughout the first year of life (Reid et al, 2006). Moreover, due to the unfused palate, some infectious diseases could occur as complications, but these typically resolve following palate repair (Jama-Alol et al, 2014; Karanth and Whittemore, 2018). A CP might have implications for feeding and speech that last well beyond the first year of life, thus resulting in increased psychological distress experienced by mothers of these infants.…”

Section: Discussionmentioning

confidence: 99%

“…Due to the unfused palate, mothers of infants with CLP or CP might experience feeding difficulties. An unfused palate can cause a high prevalence of otitis media with effusion due to Eustachian tube dysfunction (Karanth and Whittemore, 2018) leading to hearing and the potential future speech problems that might contribute to maternal concerns.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Trajectories of the Psychological Status of Mothers of Infants With Nonsyndromic Orofacial Clefts: A Prospective Cohort Study From the Japan Environment and Children’s Study

Sato

Yoshioka

Saijo

et al. 2020

The Cleft Palate-Craniofacial Journal

View full text Add to dashboard Cite

Objective: This study examined psychological status trajectories of mothers of infants with nonsyndromic orofacial clefts in Japan. Design: Prospective cohort study. Setting: Data from the Japan Environment and Children’s Study. Participants: Infants with a nonsyndromic cleft (N = 148) including cleft lip and palate (CLP; n = 72), cleft lip (CL; n = 46), and cleft palate (CP; n = 30). The control group included unaffected infants (N = 84 454). Main Outcome Measures: At 15 weeks and 27 weeks of pregnancy and 12 months after birth, the Kessler Psychological Distress Scale (clinical cutoff ≥5) was used. At 1 month and 6 months after birth, the Edinburgh Postnatal Depression Scale (clinical cutoff ≥9) was used. Results: Prenatal diagnosis rates were unavailable. Mothers of infants with CLP had higher psychological distress than controls at 27 weeks of pregnancy (prevalence ratio [PR] = 1.36, 95% CI: 1.06-1.74) and postnatal depression at 1 month after birth (PR = 2.21, 95% CI: 1.53-3.19). Mothers of infants with CP showed heightened psychological distress at 27 weeks of pregnancy (PR = 1.62, 95% CI: 1.21-2.17) and postnatal depression 6 months after birth (PR = 1.86, 95% CI: 1.01-3.43). There was no significant association between CL and maternal psychological status. At 12 months after birth, no differences in distress were found between mothers of infants with a cleft and controls. Conclusions: Mothers of infants with orofacial clefts may need psychosocial support, particularly during pregnancy and the first year after birth.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Trajectories of the Psychological Status of Mothers of Infants With Nonsyndromic Orofacial Clefts: A Prospective Cohort Study From the Japan Environment and Children’s Study

Sato

Yoshioka

Saijo

et al. 2020

The Cleft Palate-Craniofacial Journal

View full text Add to dashboard Cite

show abstract

“…Treatment with ventilation tubes (VT) are very common in children with CP±L, often at the time of the palatal repair. The optimal time for VT insertion and the risk for complications as otorrhea, myringosclerosis, retraction, perforation and granulation of the tympanic membrane, permanent hearing impairment, and post-VT insertion cholesteatoma has been discussed in many studies (Imbery et al, 2017;Karanth and Whittemore, 2018;Klockars and Rautio, 2012;Phua et al, 2009;Ponduri et al, 2009;Shaffer et al, 2018). In a systematic review by Kuo and colleagues, post-VT complications and sequelae are described in seven articles.…”

Section: Treatment With Ventilation Tubes and Risk For Following Compmentioning

confidence: 99%

“…Eustachian tube dysfunction often lasts more than 5 years after palatal repair (Bluestone et al, 2005; Alper et al, 2012). Children with CP±L are frequently treated with ventilation tubes (VTs) through the tympanic membrane, often at the time of palatal repair (Broen et al, 1996; Karanth & Whittemore, 2018; Shaffer et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

Hearing Thresholds in Young Children With Otitis Media With Effusion With and Without Cleft Palate

Tengroth

Lohmander

Hederstierna

2019

The Cleft Palate-Craniofacial Journal

View full text Add to dashboard Cite

Objective: To investigate hearing thresholds in children born with cleft palate and in children with otitis media with effusion but no cleft palate. Design: Prospective longitudinal group comparison study. Setting: University hospital. Participants: Sixteen children born with nonsyndromic cleft palate with or without cleft lip (CP±L) and 15 age-matched children with otitis media with effusion (OME) but without cleft. Main Outcome Measures: Hearing was tested at repeated occasions beginning with neonatal auditory brainstem response (ABR) at 1-4 months of age, and age-appropriate hearing tests from 9 to 36 months of age. Results: The median ABR thresholds in both groups were elevated but did not differ significantly. At 12 months of age, the median 4 frequency averages at 500-1000-2000-4000 Hz (4FA) were indicative of mild hearing loss but significantly better in the CP±L-group than in the group without cleft ( P < .01). There were no significant group-wise differences regarding the median 4FA at 24 and 36 months of age, and at 36 months, the median 4FA were normal in both groups. Both groups exhibited a significant improvement over time from the neonatal ABR thresholds to the 4FA at 36 months (CP±L-group P < .05; without CP±L-group P < .01). Conclusion: The hearing loss in children with CP±L was not more severe than among children with OME but without cleft palate; rather, at 12 months of age, the thresholds were significantly better in the CP±L-group than those in the group without cleft. The air conduction thresholds improved with age in both groups.

show abstract

“…The timing of the ventilation tube insertion and the management protocol in children with cleft palate are the main controversial issues and remain under extensive review. 9,10 Insertion of ventilation tubes in children with cleft palate can be done in a routine fashion or only when chronic effusion is present. There are no data in the literature to support early routine ventilation tube insertion in children with cleft palate in terms of the benefit of the outcome, especially when effusion is not found.…”

Section: Introductionmentioning

confidence: 99%

Long-term Outcome of the Management of Otitis Media with Effusion in Children with and Without Cleft Palate Using the House-brand Polyethylene Ventilation Tube Insertion

Ungkanont

2021

Smj

View full text Add to dashboard Cite

Objective: To study the long-term outcome of otitis media with effusion in children with and without cleft palate treated with the same protocol of ventilation tube insertion. Materials and Methods: A retrospective cohort study was conducted in eighty-five children with cleft palate and 80 children without cleft palate who had otitis media with effusion and had follow-up between 2001 and 2019. Both groups were treated with ventilation tube insertion for longstanding middle ear effusion more than 90 days. The main outcome was the cumulative incidence of surgical management, time of the indwelling ventilation tubes, conditions of the tympanic membrane, and the hearing outcome. Results: At 24 months old, 63.5% of children with cleft palate and 11.3% of children without cleft palate had their first ventilation tube insertion. Repeated surgery was done in 81.2% of children with cleft palate and 50% of children without cleft palate (p < 0.001). The median duration of the indwelling tube was 11.3 months in the children with cleft palate and 12.4 months in the non-cleft children (p = 0.82). At the end of the study, 63.7% of children without cleft palate and 43.5% of children with cleft palate had normal tympanic membrane (p = 0.009). The hearing outcomes of children with and without cleft palate were 20.7 dB and 19.3 dB, respectively. Conclusion: Children with and without cleft palate were managed under the same guideline and the hearing outcome was favorable in both groups.

show abstract

Middle-ear disease in children with cleft palate

Cited by 13 publications

References 99 publications

Trajectories of the Psychological Status of Mothers of Infants With Nonsyndromic Orofacial Clefts: A Prospective Cohort Study From the Japan Environment and Children’s Study

Trajectories of the Psychological Status of Mothers of Infants With Nonsyndromic Orofacial Clefts: A Prospective Cohort Study From the Japan Environment and Children’s Study

Hearing Thresholds in Young Children With Otitis Media With Effusion With and Without Cleft Palate

Long-term Outcome of the Management of Otitis Media with Effusion in Children with and Without Cleft Palate Using the House-brand Polyethylene Ventilation Tube Insertion

Contact Info

Product

Resources

About