Midchildhood Acne Associated with Inhaled Corticosteroids: Report of Two Cases and Review of the Literature

Liu, J B A Kristina; Antaya, Richard J.

doi:10.1111/pde.12108

Cited by 4 publications

(3 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…We could not differentiate between allergic or irritant reactions, but these could account for equal proportions of dermatitis . Consistent with previous findings, we also observed that a substantial proportion of patients had acne (19%) and telangiectasia (14%), probably because of long‐term use of products containing steroids, as certain common skin care products contain steroids, which can cause acne . It appeared that more females than males had acne, but the difference was not significant, possibly because of a small number of male subjects.…”

Section: Discussionsupporting

confidence: 74%

“…33 Consistent with previous findings, 20 we also observed that a substantial proportion of patients had acne (19%) and telangiectasia (14%), probably because of long-term use of products containing steroids, as certain common skin care products contain steroids, [34][35][36][37] which can cause acne. 38 It appeared that more females than males had acne, but the difference was not significant, possibly because of a small number of male subjects. Interestingly, our results show that age, but not sex, is associated with the clinical signs of adverse cutaneous reactions to skin care products.…”

Section: Discussionmentioning

confidence: 96%

See 1 more Smart Citation

Adverse cutaneous reactions to skin care products on the face vary with age, but not with sex

et al. 2018

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 74%

Section: Discussionmentioning

confidence: 96%

Adverse cutaneous reactions to skin care products on the face vary with age, but not with sex

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Acné de la mediana niñez predominantemente comedónico en niña de 3 años, secundario a glucocorticoide inhalado (fluticasona) ha sido reportado. 66 Uno de nosotros (G. Lizardo) trató una niña de 5 años con acné de la mediana niñez predominantemente comedónico localizado en la frente y región centrofacial (Figura 4).…”

Section: Manifestaciones Clínicasunclassified

Acné pediátrico

Castro¹,

Gutiérrez²

2021

Acta Pediatr Mex

View full text Add to dashboard Cite

El acné vulgar es una enfermedad común, inflamatoria y multifactorial de la unidad pilosebácea que afecta, primariamente, a los adolescentes; sin embargo, puede encontrarse a cualquier edad. Cuando ocurre entre el nacimiento y los 12 años se denomina acné pediátrico, el que con base en la edad de inicio se ha categorizado en acné neonatal, infantil, de la mediana niñez y preadolescente. La importancia de esta categorización reside en los procesos etiopatogénicos implicados, curso, complicaciones y pronóstico.El acné neonatal que coexiste en las primeras 8 semanas de la vida tiene excelente pronóstico y no requiere tratamiento. El acné infantil ocurre de 8 semanas a 1 año; la mayoría cursa sin complicaciones y tiene la implicación de padecer acné severo en la adolescencia. El acné de la mediana niñez aparece entre 1 y 7 años, periodo en el que virtualmente no existen hormonas adrenales ni gonadales, por lo que debe investigarse una endocrinopatía subyacente. En cambio, el acné preadolescente, entre los 7 y 12 años, es muy frecuente y considerado normal. Sin embargo, en todo paciente con síntomas y signos de hiperandrogenismo deberá investigarse un trastorno endocrinológico.El conocimiento del acné pediátrico permitirá al médico tratante o al pediatra sospechar la existencia de una enfermedad subyacente. La influencia de la dieta occidental en la severidad del acné se ha demostrado y está adquiriendo mayor relevancia. El tratamiento pronto y efectivo del acné reduce la repercusión psicosocial del paciente. Sin embargo, se requieren investigaciones futuras para determinar ese efecto en el paciente pediátrico.

show abstract

Fluticasone propionate

2015

Reactions Weekly

View full text Add to dashboard Cite

Fluticasone propionateMidchildhood acne: 2 case reports Two patients, one girl and one boy, aged 3 -5 years developed midchildhood acne following treatment with fluticasone propionate administered by face masks for asthma. Patient 1, a 3-year-old girl, presented with midfacial comedonal acne, which had persisted for 8 months.Examination revealed several open comedones with a few closed comedones affecting the midface including the cutaneous lips, lower nose and medial cheeks; scarce red papules and macules were also observed. She had a history of asthma, and was receiving fluticasone propionate 110 µg/puff, two puffs twice daily through a metered dose inhaler with spacer and face mask for 9 months. Her mother had a history of severe cystic acne. The mask was changed to a mouthpiece 2 months prior to presentation. Adapalene cream was administered with initial exacerbation of acne, and was replaced with adapalene gel with some regression. At followup, after 6 months, only a few open comedones on her nose and checks were observed with 3 to 4 red papules on the chin. Adapalene was continued.Patient 2, a 5-year-old boy, presented with inflammatory and comedonal acne primarily on his chin. Lesion onset coincided with the administration of fluticasone propionate inhaler with a face mask [dosage not stated]. Examination revealed several open comedones with a couple of red papules on his chin and lower cutaneous lip; his midforehead and glabella were severely affected with comedones. He was recently diagnosed with asthma. He had received fluticasone propionate 1 year prior with a spacer and mask for 4 months, and had experienced no skin problems. He was administered fluticasone propionate inhaler with a spacer and mask for 3 months due to wheezing exacerbation, and within 1 month of re-initiating fluticasone propionate with mask, comedonal and inflammatory acne ensued. His father and sister had a history of acne vulgaris. Adapalene and benzoyl peroxide were initiated, yet this treatment resulted in irritation, and was stopped. Fluticasone propionate was replaced with albuterol and beclomethasone dipropionate inhaler with a mouth spacer. A significant regression of acne was noted.Author comment: "In these two patients, the location and temporal relationship of the comedonal and inflammatory acne to the use of fluticasone with a mask would suggest steroid-related midchildhood acne." Liu KJ, et al. Midchildhood acne associated with inhaled corticosteroids: Report of two cases and review of the literature. Pediatric Dermatology

show abstract

Midchildhood Acne Associated with Inhaled Corticosteroids: Report of Two Cases and Review of the Literature

Cited by 4 publications

References 20 publications

Adverse cutaneous reactions to skin care products on the face vary with age, but not with sex

Adverse cutaneous reactions to skin care products on the face vary with age, but not with sex

Acné pediátrico

Fluticasone propionate

Contact Info

Product

Resources

About