Abstract:SummaryMidazolam 0.5 mg/kg was given intravenously as a sedative to 19 infants and children undergoing esophageal manometry after oral choral hydrate treatment. The lower esophageal sphincter pressure and motility were measured by manometry before and after midazolam injection. Midazolam did not change the lower esophageal sphincter pressure, blood pressure and respiratory rate of the subjects (p > 0.18), and the motility patterns. However, the mean heart rate increased by 5 beats/min after midazolam inject… Show more
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