Mid-infrared laser measurements of aqueous glucose

Guo, Bujin; Wang, Yi; Wei, Xiawei; Le, H. Q.

doi:10.1117/1.2714283

Cited by 5 publications

(6 citation statements)

References 29 publications

(59 reference statements)

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“…The reason is the complexity of the random scattering process. In contrast, under a well controlled configuration without random scattering, similar experiments allowed far more precise glucose measurement with lower concentration [32]. …”

Section: Results On Diffuse Scatter Imaging With Near-irmentioning

confidence: 99%

Semiconductor Laser Multi-Spectral Sensing and Imaging

Wang

2010

Sensors

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Multi-spectral laser imaging is a technique that can offer a combination of the laser capability of accurate spectral sensing with the desirable features of passive multispectral imaging. The technique can be used for detection, discrimination, and identification of objects by their spectral signature. This article describes and reviews the development and evaluation of semiconductor multi-spectral laser imaging systems. Although the method is certainly not specific to any laser technology, the use of semiconductor lasers is significant with respect to practicality and affordability. More relevantly, semiconductor lasers have their own characteristics; they offer excellent wavelength diversity but usually with modest power. Thus, system design and engineering issues are analyzed for approaches and trade-offs that can make the best use of semiconductor laser capabilities in multispectral imaging. A few systems were developed and the technique was tested and evaluated on a variety of natural and man-made objects. It was shown capable of high spectral resolution imaging which, unlike non-imaging point sensing, allows detecting and discriminating objects of interest even without a priori spectroscopic knowledge of the targets. Examples include material and chemical discrimination. It was also shown capable of dealing with the complexity of interpreting diffuse scattered spectral images and produced results that could otherwise be ambiguous with conventional imaging. Examples with glucose and spectral imaging of drug pills were discussed. Lastly, the technique was shown with conventional laser spectroscopy such as wavelength modulation spectroscopy to image a gas (CO). These results suggest the versatility and power of multi-spectral laser imaging, which can be practical with the use of semiconductor lasers.

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Section: Results On Diffuse Scatter Imaging With Near-irmentioning

confidence: 99%

Semiconductor Laser Multi-Spectral Sensing and Imaging

Wang

2010

Sensors

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“…Also, the power goes up 3 times, while the effective current tuning range changed increased 7 units to 10. . The Q should be larger than 2x10 6 at 2,280cm Fig. 4b.…”

Section: Threshold Currentmentioning

confidence: 89%

“…Due to strong absorption in the MIR by water, direct spectroscopic measurement of CO 2 in water has been limited to optical path lengths of only dozens of microns, and measurable concentration resolution of only 200mg/L. The high power and brightness of Quantum Cascade lasers could penetrate much deeper optical depths [6][7][8], i.e. 100s microns, and providing much higher averaging speed to achieve higher concentration resolution.…”

Section: Modulating and Modifying Qc Lasers For Chemical Sensingmentioning

confidence: 99%

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Quantum cascade laser sensors for online gas chromatography

Deev

Tang

2011

Quantum Sensing and Nanophotonic Devices VIII

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We show that QC laser could improve capillary Gas Chromatography Infrared spectroscopy resolution significantly, i.e. both Doppler limited and Doppler free resolution could be achieved. To achieve these goals, we report our latest efforts in characterizing the tuning and noise properties of Quantum Cascade (QC) lasers; novel schemes on modulation to gain largest tuning range as well as on stabilizing and locking the QC lasers are proposed, and results presented.

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“…Due to strong absorption in the MIR by water, direct spectroscopic measurement of CO 2 in water has been limited to optical path lengths of only dozens of microns, and measurable concentration resolution of only 200mg/L. The high power and brightness of Quantum Cascade lasers could penetrate much deeper optical depths [7][8][9], i.e. 100s microns, and providing much higher averaging speed to achieve higher concentration resolution.…”

Section: Modulating and Modifying Qc Lasers For Chemical Sensingmentioning

confidence: 99%

Microsensors based on quantum cascade lasers

Deev

Tang

2011

SPIE Proceedings

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We present our results on efficient coupling of Quantum Cascade Lasers (QCLs) into Whispering Gallery Resonators, Hollow Waveguide. We also present results of micro sensors using the unique properties of QCLs, e.g. online sensors for Gas Chromatography (GC). We show that because of the unique brightness properties of QCLs, we could improve GC-Infrared sensors' sensitivity to the same level as Mass Spectrometry, and with different dimension of chemical information.

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Mid-infrared laser measurements of aqueous glucose

Cited by 5 publications

References 29 publications

Semiconductor Laser Multi-Spectral Sensing and Imaging

Semiconductor Laser Multi-Spectral Sensing and Imaging

Quantum cascade laser sensors for online gas chromatography

Microsensors based on quantum cascade lasers

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