Mid-Gestation Cytokine Profiles in Mothers of Children Affected by Autism Spectrum Disorder: a Case-Control Study

Carter, Michael; Casey, Sophie; O’Keeffe, Gerard W.; Gibson, Louise; Murray, Deirdre M.

doi:10.21203/rs.3.rs-506236/v1

Cited by 1 publication

(1 citation statement)

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“…A recent paper, based on the national Swedish birth registry from 2007 to 2018, assessed that of 383 preterm infants born at a median age of 23.3 weeks, about 24% further developed ASD and 30% attention deficit hyperactivity disorder (ADHD) (77). Many attempts, including the investigation of the immune and cytokine profile of pregnant mothers (78), are in the spotlight. The early diagnosis of the autistic syndrome should encourage a prompt series of consultations and actions to safeguard children's oral health and prevent problems that may compel parents to resort to burdensome dental interventions.…”

Section: Concerns and Suggestionsmentioning

confidence: 99%

Insights on dental care management and prevention in children with autism spectrum disorder (ASD). What is new?

Zerman

Zotti²,

Chirumbolo³

et al. 2022

Front. Oral. Health

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Autistic subjects represent a severe concern to dentistry due to the considerable difficulty in managing their oral health, maintaining routine toothbrushing, and preventing dental and periodontal problems. The social and economic burden of managing dental care in autism spectrum disorder (ASD) children is particularly cumbersome for families and public and private health expenditure, especially when children reach the dentist following a late diagnosis with evident oral health problems. An early diagnosis of ASD helps dentists better address these children's oral health. Unfortunately, insufficient attention is paid to the training and education of general pediatricians, dentists, and dental hygienists, allowing them to get to approach the different clinical aspects of ASD. Usually, children diagnosed with ASD are scheduled for dental appointments like their neurotypical peers, whereas their needs are typically complex and personalized. Scant attention is also devoted to these patients by commercial manufacturers of dental products and devices for oral hygiene and prevention of caries and periodontal diseases, leaving parents without the support and often failing when they address the oral health of autistic children. The difficulties of oral care do not derive simply from the behavior of ASD patients, as is commonly assumed, and therefore cannot be overcome solely by the patience and attention of parents and dentists. Genetics, dietary habits, sensory impairments, and cognition disorders are other causes contributing in various degrees to the impact on the mood and psychological reactions of autistic children towards dentists. How can we prevent teeth caries, periodontal disorders, and other oral health impairments by properly managing ASD children? This manuscript gives an up-to-date overview of these problems and helps to provide good remarks.

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Section: Concerns and Suggestionsmentioning

confidence: 99%