Microwave surgical treatment of diseases of prostate

Microwave Surgical Treatment of the Prostate: Clinical Application of Microwave Surgery as a Tool for Improved Prostatic Electroresection

“…We have previously reported the results of a clinical trial using this method, and we found that a major advantage is the absence of hemorrhage both during or after the proce dure [1], However, we have noted some annoying prob lems when using the microwave prostate coagulation method which are similar to those associated with cryoprostatectomy. For example, prolonged catheterization is more frequently required than with ordinary TUR, because the necrotic tissue takes time to fall off [2).…”

“…Microwave prostatic coagulation by itself can cause significant destruction of prostatic tis sue and also relieve obstruction. This procedure can be used simply and safely because the depth of coagulation is controlled by the length of the radiating electrodes of the probe tip, the electrical output intensity and the duration of the microwave exposure [1]. However, ther apy by microwave prostatic coagulation alone has the problem of persistent sloughing of necrotic tissue follow ing the procedure.…”

“…A microwave tissue coagulator as employed in this study is a device which can also resect a portion of the liver [3]. We have previously reported the usefulness of this tech nique in the treatment of diseases of the prostate [1] and in bladder cancer [4]. Microwave prostatic coagulation by itself can cause significant destruction of prostatic tis sue and also relieve obstruction.…”

“…In this series the rectal temperature adjacent to the prostate was not monitored because the safety of the microwave coagulation pro cedure had been well established through prior clinical experiences [ 1 ]. The prostate was then radiated with an output of 100 W for 30 s. When the estimated prostatic weight was over 30 g by sonography or when the prostatic urethra was more than 4 cm by urethrovesicography, the procedure was repeated two or three times as the probe was gradually removed.…”

Combination Therapy with Microwave Coagulation and Intracavitary Irradiation for Bladder Cancer

“…Experimental studies have shown that when tumor cells were subjected to the microwave treatment, the cell membrane, nucleus, and intracellular granules were maintained morphologically, even in cases where cell viability was completely lost [9]. Microwave coagu lation of prostate disease has also been reported [10,11]. The area of coagulation can be adjusted easily by varying the length of the microwave radiator, electric output, coagulation time, and thickness of a coaxial cable [11].…”