Microwave enhanced silica encapsulation of magnetic nanoparticles

Park, Jeong Chan; Gilbert, Dustin A.; Liu, Kai; Louie, Angelique Y.

doi:10.1039/c2jm16595c

Cited by 24 publications

(21 citation statements)

References 42 publications

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“…First, the originally hydrophobic nanoparticles were transferred to water using a recent literature procedure. 45 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 28 temperature than that of n-hexane. Once the adequate volume of n-hexadecane was added to reach the desired approximate concentration, the vials were ultrasonicated in a water bath for 5 minutes at room temperature.…”

Section: Synthesis Of 14-nm Fe 3 O 4 Nanocubes By Seeded Growthcontrasting

confidence: 50%

Nano-objects for Addressing the Control of Nanoparticle Arrangement and Performance in Magnetic Hyperthermia

et al. 2015

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One current challenge of magnetic hyperthermia is achieving therapeutic effects with a minimal amount of nanoparticles, for which improved heating abilities are continuously pursued. However, it is demonstrated here that the performance of magnetite nanocubes in a colloidal solution is reduced by 84% when they are densely packed in three-dimensional arrangements similar to those found in cell vesicles after nanoparticle internalization. This result highlights the essential role played by the nanoparticle arrangement in heating performance, uncontrolled in applications. A strategy based on the elaboration of nano-objects able to confine nanocubes in a fixed arrangement is thus considered here to improve the level of control. The obtained specific absorption rate results show that nanoworms and nanospheres with fixed one- and two-dimensional nanocube arrangements, respectively, succeed in reducing the loss of heating power upon agglomeration, suggesting a change in the kind of nano-object to be used in magnetic hyperthermia.

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Section: Synthesis Of 14-nm Fe 3 O 4 Nanocubes By Seeded Growthcontrasting

confidence: 50%

Nano-objects for Addressing the Control of Nanoparticle Arrangement and Performance in Magnetic Hyperthermia

et al. 2015

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“…Silica is known for its biocompatibility 36, and silica coating of UCLNPs therefore offers an attractive way of functionalization 37,38. This has already been applied to a multitude of nanoparticle systems, including gold and silver NPs 39, magnetic NPs 40, and quantum dots 41. In addition, silica coating is a flexible coating technique that is applicable to both hydrophilic and hydrophobic NPs 42,43,44.…”

Section: Introductionmentioning

confidence: 99%

Multicolor Upconversion Nanoparticles for Protein Conjugation

Wilhelm¹,

Hirsch²,

Patterson³

et al. 2013

Theranostics

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We describe the preparation of monodisperse, lanthanide-doped hexagonal-phase NaYF4 upconverting luminescent nanoparticles for protein conjugation. Their core was coated with a silica shell which then was modified with a poly(ethylene glycol) spacer and N-hydroxysuccinimide ester groups. The nanoparticles were characterized by transmission electron microscopy, Raman spectroscopy, X-ray diffraction, and dynamic light scattering. The N-hydroxysuccinimide ester functionalization renders them highly reactive towards amine nucleophiles (e.g., proteins). We show that such particles can be conjugated to proteins. The protein-reactive UCLNPs and their conjugates to streptavidin and bovine serum albumin display multicolor emissions upon 980-nm continuous wave laser excitation. Surface plasmon resonance studies were carried out to prove bioconjugation and to compare the affinity of the particles for proteins immobilized on a thin gold film.

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“…A number of procedures have been reported to achieve this. Magnetic nanoparticles were transferred from organic solvents to water by using TMAOH [6]. Quantum dots prepared with trioctylphosphine and oleyamine were transferred into an aqueous solution by using surfac- tant/lipid mixtures [10].…”

Section: Resultsmentioning

confidence: 99%

“…However, magnetic nanoparticles synthesized in aqueous solutions have poor crystallinity and polydispersity, compared to the nanoparticles prepared in an organic phase. To overcome these issues, one can first generate monodisperse magnetic nanoparticles in organic solvents first and then transferred them into water by using phase transfer agents, such as tetramethylammonium hydroxide (TMAOH) and cetyltrimethylammonium bromide (CTAB) [6,7]. However, the phase transfer of core/shell nanoparticles with controlled size and surface properties from an organic phase to water has only been demonstrated to a limited degree [5].…”

Section: Introductionmentioning

confidence: 99%

Water-soluble core/shell nanoparticles for proton therapy through particle-induced radiation

Park

Jung

Kim

et al. 2015

Journal of the Korean Physical Society

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Metallic nanoparticles have been used in biomedical applications such as magnetic resonance imaging (MRI), therapy, and drug delivery systems. Metallic nanoparticles as therapeutic tools have been demonstrated using radio-frequency magnetic fields or near-infrared light. Recently, therapeutic applications of metallic nanomaterials combined with proton beams have been reported. Particle-induced radiation from metallic nanoparticles, which can enhance the therapeutic effects of proton therapy, was released when the nanoparticles were bombarded by a high-energy proton beam. Core/shell nanoparticles, especially Au-coated magnetic nanoparticles, have drawn attention in biological applications due to their attractive characteristics. However, studies on the phase transfer of organic-ligand-based core/shell nanoparticles into water are limited. Herein, we demonstrated that hydrophobic core/shell structured nanomaterials could be successfully dispersed in water through chloroform/surfactant mixtures. The effects of the core/shell nanomaterials and the proton irradiation on Escherichia coli (E. coli) were also explored.

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Microwave enhanced silica encapsulation of magnetic nanoparticles

Cited by 24 publications

References 42 publications

Nano-objects for Addressing the Control of Nanoparticle Arrangement and Performance in Magnetic Hyperthermia

Nano-objects for Addressing the Control of Nanoparticle Arrangement and Performance in Magnetic Hyperthermia

Multicolor Upconversion Nanoparticles for Protein Conjugation

Water-soluble core/shell nanoparticles for proton therapy through particle-induced radiation

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