Microwave coagulation therapy for liver cancer: laparoscopic microwave coagulation

Ido, Kenichi; Isoda, Norio; Sugano, Kentaro

doi:10.1007/s005350170121

Cited by 25 publications

(10 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…MWA can be performed percutaneously [6,7,8,9,10,11,12,13,14, 26], laparoscopically [25,38,39,40], thoracoscopically [41, 42] or at laparotomy [25, 38, 42, 43]. Whenever possible, MWA should be performed percutaneously.…”

Section: Clinical Applicationmentioning

confidence: 99%

“…The percutaneous approach is the least invasive, relatively expensive, can be performed on an outpatient basis, and can be repeated to treat recurrent tumor. Laparoscopic and thoracoscopic approaches may be employed to ablate tumors at locations inaccessible by the percutaneous approach [40, 41]. If not performed in combination with imaging techniques, they should be indicated to treat only superficially located HCC.…”

Section: Clinical Applicationmentioning

confidence: 99%

See 1 more Smart Citation

Microwave Ablation of Hepatocellular Carcinoma

2007

View full text Add to dashboard Cite

Objective: This article reviews the basic principles, equipment, current therapeutic status and future trends of microwave ablation (MWA) in the treatment of hepatocellular carcinoma (HCC). Methods: All articles published in English on MWA or MWA as a treatment for HCC were identified with a PubMed search from the 1990s through June 2007. Papers were reviewed on the technical advances of MWA equipment and the clinical applications of MWA including indications, techniques, therapeutic outcomes, complications and combination therapies. Results: MWA has several advantages, including high thermal efficiency, higher capability of coagulating blood vessels, faster ablation time, and an improved convention profile. MWA can induce large ablation volumes and yield good local tumor control, especially for small HCC. Larger HCC can also be completely ablated by using more effective antenna or simultaneous application of multiple antennae. Long-term survival comparable to that of surgery was obtained for tumors measuring 4 cm or less. Associated complications appear to be low. Conclusions: MWA is a promising minimally invasive technique for the treatment of HCC. Future advances are warranted to improve the therapeutic efficacy.

show abstract

Section: Clinical Applicationmentioning

confidence: 99%

Section: Clinical Applicationmentioning

confidence: 99%

Microwave Ablation of Hepatocellular Carcinoma

2007

View full text Add to dashboard Cite

show abstract

“…Despite a lack of prospective comparative studies, there are reports of good outcomes using LRA [10,11,12,13]. Altering the patient's body position and injecting saline solution (immersion method) not only allows good tumor visualization on ultrasonography, but also enables the physical distance between the lesion and surrounding organs such as the diaphragm and gastrointestinal tract to be maintained, thus preventing thermal injury to these organs during treatment [13,14,15]. …”

Section: Discussionmentioning

confidence: 99%

Short-Term Results of Laparoscopic Radiofrequency Ablation Using a Multipolar System for Localized Hepatocellular Carcinoma

et al. 2016

Self Cite

View full text Add to dashboard Cite

Background and Aim: Multipolar radiofrequency ablation (RFA) is feasible for the treatment of hepatocellular carcinoma (HCC) for which a large ablative area is planned, and it imposes a light physical burden on patients. Multipolar RFA via the percutaneous approach is performed in the majority of cases, but the efficacy of multipolar RFA with a laparoscopic approach has rarely been studied. This study aimed to evaluate the efficacy and safety of multipolar laparoscopic RFA (LRA) for localized HCC over the short term. Methods: From January 2014 to January 2016, 77 consecutive patients with 130 HCCs treated by multipolar LRA were assessed. One to three bipolar needle applicators were inserted under laparoscopic ultrasonography guidance, regardless of tumor location. We intended to achieve parallel insertions and no-touch ablation as much as possible. Results: The median size of the main tumor was 22 mm (range, 10-42 mm). The median follow-up time was 13.6 months (range, 3.1-24.8 months). In all cases, a sufficient ablative area was obtained as planned, without thermal injury of adjacent organs. During the follow-up period, all patients were alive with no local tumor progression, while intrahepatic recurrence distant from the primary site occurred in 7 patients. The 2-year local tumor progression-free survival rate and overall cancer-free survival rate were 100 and 81.6%, respectively. There were no procedural major complications caused prolonging the hospitalization, and all patients were discharged without subjective symptoms 4-7 days after LRA. Conclusions: Multipolar LRA was efficacious in the treatment of localized HCCs by safely achieving a good ablative area.

show abstract

“…We have used LUS extensively for the screening of lesions localized in the liver and for needle biopsies for histological diagnosis [2,10,11]. LUS is not only useful for diagnosis but also indispensable in the laparoscopic treatment of HCC [9].…”

Section: Lus Was First Attempted By Yamakawa Et Al In 1958 Tomentioning

confidence: 99%