“…Moreover, they successfully evaluated their anticancer activity against various malignant cell lines, such as HeLa, MCF7, A2780, and A43. Likewise, several approaches have been reported for steroidal-thiazole, 112 imidazolidine, 113,114 isoxazoline, 115 pyrazole, 116 oxazole, 117 tetrazole, 118 pyrazoline, 119 pyridine, 120 and pyrimidine 121 derivative syntheses. In GS chemistry, hetero-functionalized derivatives have so far been limited.…”