MICROWAVE-ASSISTED SYNTHESIS OF SCHIFF BASE AND MIXED LIGAND COMPLEXES OF Cr(III): COMPARISON WITH CONVENTIONAL METHOD AND ANTIMICROBIAL STUDIES

Abstract

The Sustainable/Greener approach is prioritized over the conventional approach because of its environment-friendly, less time-consuming, less energy-consuming, less hazardous compounds synthesis, and low expenditure. Using a greener approach involving the use of microwave, Cr complexes were synthesized from Schiff base and various bidentate ligands and compared with conventional methods. Condensing 2-amino pyridine and isatin produced Schiff base. Complexes of Cr(III) were synthesized by using some bio-potent secondary ligands with Schiff base. Both Schiff base and complexes were characterized by FTIR spectroscopy, 1H NMR spectroscopy, magnetic moment analysis, elemental investigation, etc. The synthesized compounds will be further used for biological evaluation that can be further used in drugs and agrochemical design.