Microwave Assisted Synthesis and Characterization of Silver Nanoparticles Using Ocimumbasilicum and its Anti-Inflammatory Activity against Human Blood Cells

Abstract

The present investigation was to synthesis the nanoparticles by using the medicinal plant Ocimum basilicum leaf extract and silver nitrate solution. The synthesized silver nanoparticles were analyzed by UV Spectroscopy (UV-Vis), Transmission Electron Microscopy (TEM), X-ray diffraction spectroscopy (XRD) and Fourier transform infrared spectroscopy (FTIR). The particle is found to have an average size of 14.6 nm& 13.8nm by XRD and TEM analysis respectively. The silver nanoparticles were synthesized by microwave assisted method, which was found to yield nanoparticles rapidly and easily. Further, these nanoparticles were found to exhibit AgNPs, which may also be efficiently employed in Anti-inflammatory activity of pharmaceutical research to obtain better result of plant as shown by our study. The anti-inflammatory activity of silver nanoparticles was tested and confirmed against human blood cells. Hence, the present research aims to open new avenues for the improvement of medicinal uses with the synthesis of silver nanoparticles by using Ocimum basilicum leaf extract for various ailments and to bring the anti-inflammatory medicinal plant to the scientist's notice, to educate awareness and add values to the resource.