Microwave assisted reactions of 2-[3-(Trifluoromethyl)phenyl]-4-R1-furo[3,2-b] pyrrole-5-carboxhydrazides

Gašparová, Renata; Moncman, Martin; Horváth, Branislav

doi:10.2478/s11532-008-0009-4

Cited by 5 publications

(3 citation statements)

References 16 publications

(15 reference statements)

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“…The present paper is a continuation of previous research, which dealt with the synthesis and reactions of furo[3,2-b]pyrrole system (GAŠPAROVÁ et al, 2005;GAŠPAROVÁ et al, 2007).…”

Section: Introductionmentioning

confidence: 91%

SYNTHESIS AND REACTIONS OF NEW DERIVATIVES OF FURO[3,2-b]PYRROLE

Zemanová¹,

Gašparová²

2013

Nova Biotechnologica Et Chimica

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Synthesis of methyl 4H-furo[3,2-b]pyrrole-5-carboxylate is taken place in two step synthesis. Vilsmeier-Haack reaction of 4H-furo[3,2-b]pyrrole-5-carboxylate 1 led to methyl 2-formyl-4H-furo[3,2- b]pyrrole-5-carboxylate 4, which served as starting compound for synthesis of furo[3,2-b]pyrrole-2- aldoxime 5 and methyl 2-[(4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-4H-furo[3,2-b]pyrrole-5- carboxylate 7. The hydrazinolysis of 1 was prepared by carbohydrazide 2, which subsequently reacted with aldehydes to form of derivatives 3. Pyrazole derivatives 11 were prepared by the reaction of azlactone 9 with derivatives 10. Reactions were carried out under microwave irradiation or at classical heating.

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“…The present paper is a continuation of previous research, which dealt with the synthesis and reactions of furo[3,2-b]pyrrole system (GAŠPAROVÁ et al, 2005;GAŠPAROVÁ et al, 2007).…”

Section: Introductionmentioning

confidence: 91%

SYNTHESIS AND REACTIONS OF NEW DERIVATIVES OF FURO[3,2-b]PYRROLE

Zemanová¹,

Gašparová²

2013

Nova Biotechnologica Et Chimica

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“…As part of our current studies on the development of new methods in heterocyclic synthesis, 13,14 we report an efficient synthesis of furo [3,2-b]pyrrole derivatives fused with six-membered rings and evaluation of the synthesized compounds as to their antibacterial activity.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and antibacterial activity of furo[3,2-b]pyrrole derivatives

Zemanov¹,

Gaparov²,

Bohč³

et al. 2017

Arkivoc

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“…The present study is a follow-up paper to our previous research dealing with the synthesis and reactions of furo[3,2- b ]pyrrole system [ 6 , 7 ] and the study of its biological activity. The effect of N ′-{[5-(R-phenyl)furan-2-yl]methylene}-2-[3-(trifluoromethyl)phenyl]-4 H -furo[3,2- b ]pyrrole-5-carboxhydrazides on inhibition of photosynthetic electron transport in spinach chloroplasts and chlorophyll content in the antialgal suspensions of Chlorella vulgaris was investigated [ 8 ].…”

Section: Introductionmentioning

confidence: 99%