Eur J Chem volume 9, issue 3, P269-274 2018 DOI: 10.5155/eurjchem.9.3.269-274.1751
Yousef Mohammad Hijji, Rajeesha Rajan, Hani Darwish Tabba, Imad Ali Abu-Yousef, Said Mansour, Hamdi Ben Yahia

Nitriles are versatile organic precursors in organic synthesis and have numerous applications. An efficient microwave assisted method for conversion of aromatic aldehydes to the corresponding nitriles is reported. Aldehydes are readily converted to oxime followed by acetylation and acetic acid elimination to provide nitriles in good yields within minutes. The method proved to be efficient for the synthesis of aromatic and heterocyclic nitriles. The reaction proceeds smoothly by microwave at 150 °C for 5 minutes. The obtained products are isolated simply by filtration or extraction.


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