Microwave assisted green synthesis of Hydroxyapatite nanorods using Moringa oleifera flower extract and its antimicrobial applications

Abstract

Graphical abstract

Presentation of Antibacterial and Therapeutic Anti-inflammatory Potentials to Hydroxyapatite via Biomimetic With Azadirachta indica: An in vitro Anti-inflammatory Assessment in Contradiction of LPS-Induced Stress in RAW 264.7 Cells

“…In support of our study, Kalaiselvi et al (2018) synthesized HA nanorods using the flower extract of Moringa oleifera and observed the potent antibacterial activity on Gram-positive bacteria ( Bacillus subtilis , Monococcus luteus , and S. aureus ) and Gram-negative bacteria ( Klebsiella pneumoniae , Pseudomonas aeruginosa , and Salmonella paratyphi ). Likewise, Scatolini et al (2018) tested biomimetic HA with different Brazilian propolis and noticed potent antibacterial activity on S. aureus ATCC 25923 in the range of >12.5 to >100 μg/ml for MIC and >206.7–800 μg/ml for MBC.…”

“…Insight of the aforementioned demerits, biomimetic of HA composite with potent antibacterial and anti-inflammatory bioresources could be highly preferred and recommended over chemical substances for orthopedic implants. In the current scenario, plant sources are highly preferred due to their non-toxicity and eco-friendliness (Kalaiselvi et al, 2018; Phatai et al, 2019). Therefore, the biomimetic of HA with plant sources could be highly appropriate and satisfactory.…”

Coupled effect of particle size of the source materials and calcination temperature on the direct synthesis of hydroxyapatite

“…However, the % of carbonate content in the Hap samples was calculated from the FT-IR data as described in the following §3. Next, to examine the effect of mesh size together with the calcination temperature on the crystallographic properties of Hap, the crystallite size (D c ), crystallinity degree (Xc) and crystallinity index (CI), dislocation density (δ) and micro-strain (ε) of all the Hap samples were calculated using well-established equations [30,31] and summarized in table 1.…”

An innovative Azadirachta indica gum‐mediated synthesis of cocoon‐shaped nano‐AgHAp from Lamellidens marginalis shells

“…Most of the synthetic methods require toxic organic solvents for the preparation of HAp. To minimize the usage of organic solvents, HAp nanoparticles have been synthesized using green extract as a template medium, which is highly advantageous because of its low cost, ecofriendly, and less toxicity 22,23 . On the other hand, several attempts have been made for the fabrication of biofunctional nanoparticles through simple and efficient synthesis method with specific morphological changes.…”

“…To minimize the usage of organic solvents, HAp nanoparticles have been synthesized using green extract as a template medium, which is highly advantageous because of its low cost, ecofriendly, and less toxicity. 22,23 On the other hand, several attempts have been made for the fabrication of biofunctional nanoparticles through simple and efficient synthesis method with specific morphological changes. The mediated synthesis using plant extract has gained emerging interest as an active research area in nanotechnology.…”