Microvascular Response in the Periodontal Ligament Following Mucoperiosteal Flap Surgery

Abstract

When the mucoperiosteal flap was elevated, active wound healing was activated because of angiogenesis from the PDL, which possesses a microcirculatory system. Moreover, it was suggested that angiogenesis of the PDL vascular plexus and subsequent bone resorption of alveolar bone might temporarily reduce the tooth-supporting function and cause postoperative mobility.

Single Flap Approach With and Without Guided Tissue Regeneration and a Hydroxyapatite Biomaterial in the Management of Intraosseous Periodontal Defects

“…The flap can be easily stabilized to the undetached papilla optimizing wound closure for primary intention healing. Moreover, leaving a great volume of supracrestal gingival tissues intact may better preserve the interdental vascular supply 20‐22 . Wound stabilization and preservation of an intact interdental papilla may also contribute to improved preservation of esthetics 9 .…”

Strain Reduction of Human Gingival Fibroblasts Induces the ATP Pathway

“…As bone remodeling is a localized process, the local release of ATP from HGF cells may play a critical role in local alveolar crest bone remodeling [20,33,34]. Further, our findings suggest that local increase of extracellular ATP initiates a sequenced chain of reactions leading to increased expression of RANK-L that activate osteoclasts specifically on the PDL aspect of alveolar bone [35]. P2X receptors have been implicated in the generation of osteoclasts via up-regulation of osteoblast-expressed receptor, an activator of nuclear factor-B ligand (RANK-L), and an important link in the formation and activation of osteoclasts by several group of investigators [16,36].…”

Clinical and Systemic Effects of Periodontally Accelerated Osteogenic Orthodontics: A Pilot Study

“…They are based on a minimally invasive approach with a flap elevation only on one side (buccal or lingual) leaving the soft tissues on the opposite side intact, facilitating flap repositioning and suturing with the undetached oral papilla thus optimizing wound closure for primary intention. Moreover, by leaving a great volume of supracrestal soft tissues intact, better preservation of the blood supply in the interdental area may eventually occur (Binderman et al, 2001;Nobuto et al, 2003Nobuto et al, , 2005.…”