Microvascular diabetic complications are more prevalent in India compared to Mauritius and the UK due to poorer diabetic control

Potluri, Rahul; Purmah, Yanish; Dowlut, Mohammad; Sewpaul, Nilesh; Lavu, Deepthi

doi:10.1016/j.diabres.2009.08.008

Cited by 25 publications

(15 citation statements)

References 2 publications

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“…It has been shown that DR is more prevalent in India compared to Whites, due to poorer diabetic control. 49 Evaluation of the factors associated with DR in suboptimal conditions in other population groups will be interesting, so that it can be known whether these factors also vary in different ethnicities/races.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Risk Factors of Diabetic Retinopathy in Subjects with Suboptimal Glycemic, Blood Pressure and Lipid Control. Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetic Study (SN-DREAMS, Report 33)

Raman

Gupta

Kulothungan

et al. 2012

Current Eye Research

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Section: Discussionmentioning

confidence: 99%

Prevalence and Risk Factors of Diabetic Retinopathy in Subjects with Suboptimal Glycemic, Blood Pressure and Lipid Control. Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetic Study (SN-DREAMS, Report 33)

Raman

Gupta

Kulothungan

et al. 2012

Current Eye Research

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“…Another study of central government employees in Agra, north India, found that increased fasting plasma glucose (FPG) was an independent risk factor for CKD (OR 4.18 for FPG >8 mmol/L) . Several clinic‐based studies from different parts of India have reported on the prevalence of nephropathy in patients with diabetes, with prevalence ranging from 15% to 35% (Table ) . The population‐based Chennai Urban Rural Epidemiology Study reported a prevalence of 26.9% for microalbuminuria (MiAU) and 2.2% for overt nephropathy (defined as macroalbuminuria [MaAU] and the presence of retinopathy) .…”

Section: Diabetic Nephropathymentioning

confidence: 99%

“…17 Several clinic-based studies from different parts of India have reported on the prevalence of nephropathy in patients with diabetes, with prevalence ranging from 15% to 35% (Table 2). [18][19][20][21][22][23][24][25][26][27][28][29] The population-based Chennai Urban Rural Epidemiology Study reported a prevalence of 26.9% for microalbuminuria (MiAU) and 2.2% for overt nephropathy (defined as macroalbuminuria [MaAU] and the presence of retinopathy). 26 In that study, HbA1c, duration of diabetes, and systolic blood pressure were associated with both MiAU and overt nephropathy.…”

Section: Diabetic Nephropathymentioning

confidence: 99%

Epidemiology of microvascular complications of diabetes in South Asians and comparison with other ethnicities

Gupta

Misra

2016

Journal of Diabetes

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Type 2 diabetes mellitus is widely prevalent in South Asians, and has a significant effect on health, as well as the economies of South Asian countries, particularly when the disease is associated with complications. There are certain characteristics associated with the South Asian phenotype that make South Asians especially prone to diabetes, as well as its complications. Microvascular complications cause considerable morbidity and mortality. There are significant differences in the epidemiology of microvascular complications between South Asians and people of other races. There is evidence of higher prevalence of nephropathy and retinopathy in South Asians compared with Caucasians; however, recent studies indicate that this trend seems to be leveling off. Importantly, diabetic neuropathy occurs less frequently in South Asians compared with Caucasians. These observations have important implications in managing South Asian patients with diabetes and microvascular complications.

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“…The acute complications of diabetes mellitus include diabetic ketoacidosis coma, hyperosmolar nonketotic coma, hypoglycemia coma, and lactic acidosis coma. Chronic complications of type 2 diabetes can be classified as macrovascular (coronary artery disease, peripheral artery disease, and cerebrovascular disease) and microvascular (diabetic nephropathy, retinopathy, and neuropathy) (Potluri et al 2009). …”

Section: Introductionmentioning

confidence: 99%

PON1 55 and 192 Gene Polymorphisms in Type 2 Diabetes Mellitus Patients in a Turkish Population

et al. 2010

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Diabetes mellitus is a multifactorial metabolic disease, caused by the complete or relative absence of insulin hormone, which results in the deterioration of carbohydrate, protein, and lipid metabolism. The PON1 55 and 192 polymorphisms have been reported to be associated with type 2 diabetes and its complications. In this study, the involvement of the PON1 55 and 192 polymorphisms and paraoxonase enzyme activity in diabetic complications was assessed. The MM and QQ genotypes were the most frequent in complications of type 2 diabetes in both of the polymorphisms. PON enzyme activity was lower in the type 2 diabetes group with respect to the control group. Regarding both genotypes and enzyme activity, correlations were found between the PON1 55 and 192 genotypes and diabetic complications. This study thus helps to outline a genotype-phenotype relation for the PON1 gene in a Turkish population.

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Microvascular diabetic complications are more prevalent in India compared to Mauritius and the UK due to poorer diabetic control

Cited by 25 publications

References 2 publications

Prevalence and Risk Factors of Diabetic Retinopathy in Subjects with Suboptimal Glycemic, Blood Pressure and Lipid Control. Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetic Study (SN-DREAMS, Report 33)

Prevalence and Risk Factors of Diabetic Retinopathy in Subjects with Suboptimal Glycemic, Blood Pressure and Lipid Control. Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetic Study (SN-DREAMS, Report 33)

Epidemiology of microvascular complications of diabetes in South Asians and comparison with other ethnicities

PON1 55 and 192 Gene Polymorphisms in Type 2 Diabetes Mellitus Patients in a Turkish Population

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