Microvascular decompression of the trigeminal nerve in the treatment of SUNCT and SUNA

Williams, Max; Bazina, Renata; Tan, Leong; Rice, Hal; Broadley, Simon

doi:10.1136/jnnp.2009.182824

Cited by 38 publications

(45 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Growing evidence also supports aetiological similarities with trigeminal neuralgia because of the significant proportions of patients with SUNCT and SUNA showing a neurovascular conflict with the trigeminal nerve [4]. Preliminary data demonstrate the efficacy of MVD of the trigeminal nerve in SUNCT and SUNA, suggesting the possible role of damage to the trigeminal sensory root in the pathophysiology of these disorders [39]. This underlying common mechanism could account for the striking clinical similarities between these conditions, supporting the hypothesis that SUNCT, SUNA and trigeminal neuralgia represent variants of the same disorder.…”

Section: Resultsmentioning

confidence: 88%

SUNCT, SUNA and trigeminal neuralgia

Lambru¹,

Matharu²

2014

Current Opinion in Neurology

View full text Add to dashboard Cite

Despite being considered distinct conditions, emerging clinical and radiological evidence supports a broader nosological concept of SUNCT, SUNA, and trigeminal neuralgia. These conditions may constitute a continuum of the same disorder, rather than separate clinical entities. Further evidence is required to shed light on this nosological issue, given its potential impact on clinical practice and further research studies in this area.

show abstract

Section: Resultsmentioning

confidence: 88%

SUNCT, SUNA and trigeminal neuralgia

Lambru¹,

Matharu²

2014

Current Opinion in Neurology

View full text Add to dashboard Cite

show abstract

“…This supported the notion of MVD being a potential treatment for these conditions. To date, 10 case reports and a case series of nine patients with medically intractable SUNCT and SUNA patients, who underwent MVD of the trigeminal nerve, have been reported [26,[30][31][32][33][34][35]. After a median follow-up of 14 months (range 0.5-32 months), 12 of 19 (63 %) of cases were pain free, whereas in the remaining patients, the procedure had little or no effect.…”

Section: Microvascular Decompression Of the Trigeminal Nervementioning

confidence: 99%

SUNCT and SUNA: medical and surgical treatments

Lambru

Matharu

2013

Neurol Sci

View full text Add to dashboard Cite

Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) and short-lasting unilateral neuralgiform headache attacks with cranial autonomic symptoms (SUNA) are rare and often disabling primary headache disorders. Their management can be challenging. The abortive therapies are not generally useful as the attacks are relatively short lasting. A myriad of pharmacological preventive treatments have been tried in single case reports or small series in an openlabel fashion. Lamotrigine, as an oral preventive treatment, and lidocaine, as an intravenous transitional treatment, seem to be the most effective therapies. For medically intractable chronic forms of SUNCT and SUNA, several surgical approaches have been tried. These include ablative procedures involving the trigeminal nerve or the Gasserian ganglion, microvascular decompression of the trigeminal nerve, and neurostimulation techniques. This review provides an overview of the current pharmacological and surgical options for SUNCT and SUNA syndromes.

show abstract

“…Willams et al described 9 patients with vascular compression of the trigeminal nerve who underwent decompressive surgery and reported that 6 of the 9 patients were rendered pain-free. The remaining patients did not have any observed benefit [31]. Additional cases have been reported of patients attaining pain freedom from microvascular decompression [32][33][34].…”

Section: Trigeminal Nerve Decompressionmentioning

confidence: 95%

“…Despite reported good outcomes, it is important to consider potential adverse events for such invasive procedures used in the treatment of SUNCT and SUNA. In the case series by Williams et al, 1 patient suffered ipsilateral hearing loss post procedure [31]. Black and Dodick identified 2 patients who had undergone both gamma knife radiosurgery and microvascular decompression without sustained benefit.…”

Section: Trigeminal Nerve Decompressionmentioning

confidence: 99%

SUNCT/SUNA: A Review

Pomeroy

Nahas

2015

Curr Pain Headache Rep

View full text Add to dashboard Cite

Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) and short-lasting neuralgiform headache attacks with cranial autonomic features (SUNA) are rare headache disorders characterized by severe, short-lasting headaches. These headache disorders are often refractory to treatment and can be secondary phenomena. This article reviews the history, pathophysiology, and treatment of these disorders. Both pharmacotherapy and procedural interventions are discussed in context of historical and more recent reports.

show abstract

Microvascular decompression of the trigeminal nerve in the treatment of SUNCT and SUNA

Abstract: Medically intractable SUNCT and SUNA subjects with a demonstrable aberrant arterial loop impinging on the trigeminal nerve on neuroimaging may benefit from microvascular decompression.

Cited by 38 publications

References 25 publications

SUNCT, SUNA and trigeminal neuralgia

SUNCT, SUNA and trigeminal neuralgia

SUNCT and SUNA: medical and surgical treatments

SUNCT/SUNA: A Review

Contact Info

Product

Resources

About