Microvascular Complications and Their Associated Risk Factors Among Rural Type 2 Diabetic Population: A Cross-Sectional Study

Pelluri, Ranakishor; Kongara, Srikanth; Chimakurthy, Jithendra; Nagasubramanian, Vanitha Rani

doi:10.1007/s42399-021-00786-7

Cited by 4 publications

(4 citation statements)

References 16 publications

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“…In our study, Prevalence of Diabetes microvascular complications among the study participants were 56.78%, 25.3% and 14.7% for neuropathy, retinopathy and nephropathy respectively. The proportion is higher as compared to other studies (27,28). This study mainly focused on participants living in the rural area unlike other studies.…”

Section: Discussionmentioning

confidence: 81%

Associations between Diabetes Self-Management and Microvascular Complications Among Patients Living in Rural Areas, in Kenya

Ireri,

Kikuvi,

mambo

et al. 2024

Preprint

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Introduction Diabetes is a major public health concern worldwide. Low and middle-income countries are the most affected. Diabetes self-management can significantly reduce the burden of diabetes complications and mortality. Methods This cross-sectional study was conducted at the outpatient department of a county referral hospital in Kenya, from 1st August 2022 to 30th October 2022. Patients with known type II diabetes of age ≥20 years visiting the hospital for routine follow-up visits were included. A 7-tem Summary of Diabetes Self-care Activities (SDSAC) Questionnaire was used to assess Diabetes self-care activities. For data entry and statistical analysis, SPSS for Windows version 27.0 was used. Results There were 96 (39.2%) males and 149 (60.8%) females. Most of the participants were more than 61 years 148 (60.4%). Prevalence of Diabetes microvascular complications among the study participants was 56.78%, 25.3%, and 14.7% for neuropathy, retinopathy, and nephropathy respectively. significant association was found between the sum scale scores of dietary activities, blood glucose testing, physical activity, foot care, and neuropathy at 95% CI and (P< 0.001). Scores on the Blood glucose testing and foot care activities subscale were significantly associated with Retinopathy (p<0.001). Additionally, significant associations were found between the presence of nephropathy and dietary activities, f00t care, and physical activity subscale (p=<0.oo1). Conclusions Diabetes self-management activities have an impact on microvascular complications in patients with diabetes.

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Section: Discussionmentioning

confidence: 81%

Associations between Diabetes Self-Management and Microvascular Complications Among Patients Living in Rural Areas, in Kenya

Ireri,

Kikuvi,

mambo

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…T2DM is a major and growing epidemic lifestyle disease. Microvascular complications such as DR, DKDN, and DN are the major long-term complications increasing in parallel, affecting approximately 30% of patients with type 1 diabetes mellitus (T1DM) and 40% of patients with T2DM [ 16 ]. Glucocorticoid secretion was thought to be a possible link between insulin resistance and metabolic syndrome (hypertension, obesity, coronary heart disease, hyperlipidemia and type two diabetes) in patients with type 2 diabetes [ 17 , 18 ].…”

Section: Discussionmentioning

confidence: 99%

Relationship between cortisol and diabetic microvascular complications: a retrospective study

Sun,

Wang

2023

Eur J Med Res

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Objective We aimed to investigate whether serum cortisol associate with diabetic microvascular compliments in patients with type 2 diabetes mellitus (T2DM). Materials and methods The subjects were recruited from hospitalized patients with T2DM from 2019 to 2021. The odds ratios (OR) and corresponding 95% confidence intervals (CI) in relation to cortisol quartiles were obtained by multiple logistic regression analysis. Results (1) Cortisol level was positively correlated with the severity of microalbuminuria. The OR (95% CI) of microalbuminuria and macroalbuminuria in the last quartile were 3.396 (2.030, 5.682) and 8.407 (3.726, 18.971) compared with the first quartile (p < 0.001). (2) Cortisol level was positively correlated with the severity of diabetic retinopathy (DR). The OR (95% CI) of non-proliferative diabetic retinopathy group (NPDR) and proliferative diabetic retinopathy group (PDR) in the last quartile were 2.007 (1.401, 2.875) and 7.122 (2.525, 20.090) compared with the first quartile. (3) Elevated cortisol level was associated with diabetic peripheral neuropathy. The OR (95% CI) of diabetic peripheral neuropathy (DPN) in the last quartile was 1.956 (1.371, 2.792) and that in the third quartile was 1.854 (1.319, 2.608). Conclusions High serum cortisol levels were significantly associated with diabetic microvascular compliments in inpatients. Its causality remains to be further studied. Clinical trial registration number: ChiCTR2100051749.

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“…The prevalence of diabetes has increased many fold in recent decades worldwide, yet among major NCDs, it has usually been underestimated in terms of the cause of death. Diabetes is considered to have little impact on mortality directly when compared to morbidity as it mainly expedites the risk of microvascular complications [ 2 ] and various other severe chronic conditions [ 3 ]. Only a minority of patients uniquely die due to diabetes [ 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

Risk of diabetes and expected years in life without diabetes among adults from an urban community in India: findings from a retrospective cohort

Sharma,

Dilip,

Kulkarni

et al. 2024

BMC Public Health

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Background Diabetes prevalence has increased over the past few decades, and the shift of the burden of diabetes from the older population to the younger population has increased the exposure of longer durations in a morbid state. The study aimed at ascertaining the likelihood of progression to diabetes and to estimate the onset of diabetes within the urban community of Mumbai. Methods This study utilized an observational retrospective non-diabetic cohort comprising 1629 individuals enrolled in a health security scheme. Ten years of data were extracted from electronic medical records, and the life table approach was employed to assess the probability of advancing to diabetes and estimate the expected number of years lived without a diabetes diagnosis. Results The study revealed a 42% overall probability of diabetes progression, with age and gender variations. Males (44%) show higher probabilities than females (40%) of developing diabetes. Diabetes likelihood rises with age, peaking in males aged 55–59 and females aged 65–69. Males aged 30–34 exhibit a faster progression (10.6 years to diagnosis) compared to females (12.3 years). Conclusion The study’s outcomes have significant implications for the importance of early diabetes detection. Progression patterns suggest that younger cohorts exhibit a comparatively slower rate of progression compared to older cohorts.

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Microvascular Complications and Their Associated Risk Factors Among Rural Type 2 Diabetic Population: A Cross-Sectional Study

Cited by 4 publications

References 16 publications

Associations between Diabetes Self-Management and Microvascular Complications Among Patients Living in Rural Areas, in Kenya

Associations between Diabetes Self-Management and Microvascular Complications Among Patients Living in Rural Areas, in Kenya

Relationship between cortisol and diabetic microvascular complications: a retrospective study

Risk of diabetes and expected years in life without diabetes among adults from an urban community in India: findings from a retrospective cohort

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