Microtubular structure impairment after GSM-modulated RF radiation exposure

Abstract

The objective of the study was to investigate whether low-level 915 MHz GSM-modulated radiofrequency (RF) radiation impairs microtubular structure and affects normal cell growth. V79 cells were exposed to a GSM-modulated field in a Gigahertz Transversal Electromagnetic Mode cell (GTEM cell) for 1, 2, and 3 h. Signal generator combined with power and chip modulator generated the electromagnetic field (EMF). The electric field strength was adjusted to 10, 20, and 30 V/m, and the average specific absorption rate (SAR) was calculated to be 0.23, 0.8, and 1.6 W/kg. The structure of microtubule proteins was assessed by indirect immunocytochemistry, and cell growth was determined based on cell counts taken every day over six post-exposure days. Three-hour radiation exposure significantly altered microtubule structure regardless of the electric field strength. Moreover, on the third post-exposure day, three-hour radiation significantly reduced cell growth, regardless of field strength. The same was observed with two-hour exposure at 20 and 30 V/m. In conclusion, 915 MHz GSM-modulated RF radiation affects microtubular proteins in a time-dependent manner, which, in turn, affects cell proliferation. Our future research will focus on microtubule structure throughout the cell cycle and RF radiation effects on mitotic spindle.

The Biocompatibility of Wireless Power Charging System on Human Neural Cells

“…This observation is in conformity with [58]. Most experiments were focused on the effect of EMF on tubular structures [59,60]. However, the results were discussable, mostly depending on EMF.…”

Transcriptomic and metabolomic studies on the protective effect of molecular hydrogen against nuclear electromagnetic pulse-induced brain damage

“…Microtubular structure plays a key role in myelination, neuronal cytoskeletal junction, and cell-matrix attachment and has a dramatic effect on brain stiffness ( 26 ). The microtubular structure is also susceptible to EMR, and 915 MHz radiofrequency EMR can disrupt microtubule structures and perturb cell growth ( 27 ). Our transcriptomics data showed that NEMP exposure has the most significant effect on microtubular structures, with biological process terms including axoneme assembly, microtubule bundle formation, microtubule cytoskeleton organization, microtubule-based process, etc.…”