Abstract:Micro-computed tomography (micro CT) is a high-resolution radiographic modality that has been widely used in bone-tissue research. This study assessed whether there is an agreement between the manual and predefined region-of-interest (ROI) definition methods during the three-dimensional analysis of bone defects by micro-CT. Bone defects of 2.3 mm in diameter were created in the left tibiae of Wistar rats. After 14 days, the tibiae were collected and scanned. During the analysis by CtAnalyser® software, the ROI… Show more
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