This paper presented a double-open multidirectional forging with relatively few deformation passes and a uniform deformation. The constitutive equation and dynamic recrystallization model of the GH4169 superalloy were identified based on a thermal compression test and imported into Deform simulation software. The microstructure evolution law of GH4169 superalloy undergoing double-open multidirectional forging was simulated. The evolution of the recrystallization volume fraction and recrystallized grain size of the GH4169 superalloy during double-open multidirectional forging was obtained.Both higher temperatures and more passes were found to produce more complete recrystallization and smaller recrystallization grain size. At the maximum temperature studied, 1000 • C, with nine passes, the recrystallization volume fraction exceeded 95%, and the recrystallized grain size reached 3-5.5 µm.