Microstructure, biodegradation, antibacterial and mechanical properties of ZK60-Cu alloys prepared by selective laser melting technique

Shuai, Cijun; Liu, Long; Zhao, Ming-Chun; Feng, Pei; Guo, Wang; Gao, Chengde; Yuan, Fulai

doi:10.1016/j.jmst.2018.02.006

Cited by 88 publications

(43 citation statements)

References 48 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The released Cu ions contacted the bacteria on the surface of microwave-sintered Fe-Cu samples. Cu ions extracted electrons from bacteria and damaged the permeability of bacterial cell membrane, resulting in the loss of bacterial cytoplasm [ 16 ]. Cu ions and hydroxyl ions could interact with the thiol groups of the bacterial proteins, which could induce the rupture of the ionic bonds of proteins and lead to the inactivation of the proteins.…”

Section: Resultsmentioning

confidence: 99%

“…The degradation rate of Fe-based alloys may be increased by the addition of noble alloying elements to form small precipitates to produce micro-galvanic corrosion with the Fe matrix [ 12 , 13 ]. On the other hand, surgical infection may occur for medical implants [ 14 , 15 , 16 ]. Avoiding and effectively treating such an infection has become an urgent problem in the medical field, as is the abuse of antibiotics that may lead to the increase of bacterial resistance and thus is not the best way to effectively treat infections.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Study on a Novel Biodegradable and Antibacterial Fe-Based Alloy Prepared by Microwave Sintering

et al. 2021

View full text Add to dashboard Cite

This research produced a porous Fe-8 wt.% Cu alloy by microwave sintering in order to achieve (i) an increased biodegradation rate, and (ii) an antibacterial function. The Fe-8Cu alloy had higher density, hardness and degradation rate (about 2 times higher) but smaller and fewer surface pores, compared to the pure Fe. The Fe-8Cu alloy had a strong antibacterial function (the antibacterial rates against E. coli were up to 99.9%) and good biocompatibility. This work provides a novel approach of alloy design and processing to develop novel antibacterial Fe-based alloys.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Study on a Novel Biodegradable and Antibacterial Fe-Based Alloy Prepared by Microwave Sintering

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Selective laser melting (SLM) may effectively refine grain size and homogenize microstructure because of rapid cooling [10] . Although the antibacterial and corrosion resistance of Cu-containing Mg alloys had been studied [4][5]11] , never before has Cu-containing ZK30 prepared by SLM has been extensively studied.…”

Section: Introductionmentioning

confidence: 99%

Improved biodegradation resistance by grain refinement of novel antibacterial ZK30-Cu alloys produced via selective laser melting

Zhao

et al. 2019

Materials Letters

Self Cite

View full text Add to dashboard Cite

Cu-containing Mg alloys are a novel type of antibacterial biomaterial based on biodegradation of Mg and antibacterial functions of Cu. However, fast degradation limits their clinical application. For the first time, this work utilizes the synergistic effects of biodegradation of ZK30, antibacterial function of Cu and grain refinement by selective laser melting (SLM) to prepare high-performance antibacterial ZK30-Cu alloys. The obtained alloys have an improved biodegradation resistance, which is attributed to remarkable grain refinement by SLM. Furthermore, the alloys exhibit good antibacterial ability and cytocompatibility.

show abstract

“…Figure 6 shows the clinical requirements for bone cement and the corresponding designing strategies of PMCs. Proper content of Mg particles with a selected diameter, composition and degradation rate should be added to achieve good handling, compressive strength and degradation properties Meanwhile, Mg particles alloyed with bio-functional elements [29,[43][44][45] should be primarily considered to endow the PMCs with various bio-functions, such as osseointegration, osteogenic, angiogenic and antibacterial capabilities. Future work will focus on the optimization of PMCs following the strategies proposed in Fig.…”

Section: Resultsmentioning

confidence: 99%

Fabrication and Characterizations of Metallic Mg Containing PMMA-Based Partially Degradable Composite Bone Cements

Lin

Chan

Tan

et al. 2018

Acta Metall. Sin. (Engl. Lett.)

View full text Add to dashboard Cite

Inadequate strength at the bone/cement interface is one of the main drawbacks of poly(methylmethacrylate) (PMMA) bone cement in the current orthopedic surgeries. In the present work, a partially degradable PMMA/Mg composite bone cement (PMC) was developed for enhancing the bone/cement interfacial strength, which is proposed to be accomplished by increasing the osteo-conductivity of PMMA and enhancing the mechanical interlocking between bone tissue and the porous PMMA surface formed by the degradation of Mg on the surface of the cement. PMCs were prepared with various concentrations of Mg particles with different sizes and alloy compositions. The effects of Mg particle size, composition and content on the injectability, mechanical and degradation properties, and biocompatibility of PMCs were evaluated. The results show that these parameters affected the properties of the PMCs simultaneously. The good injectability and compressive strengths of PMMA were preserved, while the compatibility to osteoblasts was enhanced when adding Mg particles in a proper manner. The PMCs degraded at the surface with time and formed porous surface structures in the physiological environment, while maintaining the original compressive strengths. This preliminary study shows that the PMC is promising for minimally invasive orthopedic surgery; however, it still requires to be optimized and evaluated in the future.

show abstract

Microstructure, biodegradation, antibacterial and mechanical properties of ZK60-Cu alloys prepared by selective laser melting technique

Cited by 88 publications

References 48 publications

Study on a Novel Biodegradable and Antibacterial Fe-Based Alloy Prepared by Microwave Sintering

Study on a Novel Biodegradable and Antibacterial Fe-Based Alloy Prepared by Microwave Sintering

Improved biodegradation resistance by grain refinement of novel antibacterial ZK30-Cu alloys produced via selective laser melting

Fabrication and Characterizations of Metallic Mg Containing PMMA-Based Partially Degradable Composite Bone Cements

Contact Info

Product

Resources

About