This study reports that small amounts of MoO 3 multilayer ribbon crystal (MoO 3 MLRC) in Ni 3 Al intermetallics showed the decreased friction coefficients and improved wear resistance at different contact loads. Specifically, the friction coefficients (0.32-0.34) and wear rates [(2-4) 9 10 -5 mm 3 N -1 m -1 ] are significantly reduced for Ni 3 Al at 2-8 N. A possible explanation for the friction and wear reduction is that MoO 3 MLRC as a multilayer material shears easily in the tribo-layer during the sliding contact, and provides low friction. In addition, this MoO 3 MLRC with excellent bending strength is found to dissipate shear stress and suppress severe plastic deformation under a cyclic stress, thus drastically improving wear resistance of Ni 3 Al.