Key parameters for a thermomechanically controlled processing and accelerated cooling process (TMCP-AcC) were determined for integrated mass production to produce extra high-yieldstrength microalloyed low carbon SiMnCrNiCu steel plates for offshore structure and bulk shipbuilding. Confocal scanning microscopy was used to make in-situ observations on the austenite grain growth during reheating. A Gleeble 3800 thermomechanical simulator was employed to investigate the flow stress behavior, static recrystallization (SRX) of austenite, and decomposition behavior of the TMCP conditioned austenite during continuous cooling. The Kocks-Mecking model was employed to describe the constitutive behavior, while the JohnsonMehl-Avrami-Kolmogorov (JMAK) approach was used to predict the SRX kinetics. The effects of hot rolling schedule and AcC on microstructure and properties were investigated by test-scale rolling trials. The bridging between the laboratory observations and the process parameter determination to optimize the mass production was made by integrated industrial production trials on a set of a 5-m heavy plate mill equipped with an accelerated cooling system. Successful production of 60-and 50-mm-thick plates with yield strength in excess of 460 MPa and excellent toughness at low temperature (213 K (-60°C)) in the parent metal and the simulated coarse-grained heat affected zone (CGHAZ) provides a useful integrated database for developing advanced high-strength steel plates via TMCP-AcC.