Microsphere Polymers in Molecular Imprinting: Current and Future Perspectives

Abstract

Molecularly imprinted polymers (MIPs) are specific crosslinked polymers that exhibit binding sites for template molecules. MIPs have been developed in various application areas of biology and chemistry; however, MIPs have some problems, including an irregular material shape. In recent years, studies have been conducted to overcome this drawback, with the synthesis of uniform microsphere MIPs or molecularly imprinted microspheres (MIMs). The polymer microsphere is limited to a minimum size of 5 nm and a molecular weight of 10,000 Da. This review describes the methods used to produce MIMs, such as precipitation polymerisation, controlled/‘Living’ radical precipitation polymerisation (CRPP), Pickering emulsion polymerisation and suspension polymerisation. In addition, some green chemistry aspects and future perspectives will also be given.

Unraveling the mystery of efficacy in Chinese medicine formula: New approaches and technologies for research on pharmacodynamic substances

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Solid-Phase Extraction of Active Compounds from Natural Products by Molecularly Imprinted Polymers: Synthesis and Extraction Parameters

“…The reusability and stability of the imprinted material play a significant role in producing an economic, dependable, sustainable, and ecologically friendly strategy, according to Orowitz et al [67]. Polymer degradation compounds are well-known for contaminating samples during their application.…”

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