Microscopy and biomimetics: the NanoSuit® method and image retrieval platform

Abstract

This review aims to clarify a suitable method towards achieving next-generation sustainability. As represented by the term ‘Anthropocene’, the Earth, including humans, is entering a critical era; therefore, science has a great responsibility to solve it. Biomimetics, the emulation of the models, systems and elements of nature, especially biological science, is a powerful tool to approach sustainability problems. Microscopy has made great progress with the technology of observing biological and artificial materials and its techniques have been continuously improved, most recently through the NanoSuit® method. As one of the most important tools across many facets of research and development, microscopy has produced a large amount of accumulated digital data. However, it is difficult to extract useful data for making things as biomimetic ideas despite a large amount of biological data. Here, we would like to find a way to organically connect the indispensable microscopic data with the new biomimetics to solve complex human problems.

Association between human papillomavirus particle production and the severity of recurrent respiratory papillomatosis

“…Since HPV DNA is detected in the laryngeal mucosa of patients in remission, it is believed that persistent HPV infection is involved in the pathogenesis of RRP 13 . However, no reports have examined the association between HPV involvement (or the state of HPV particles produced by tumours) and disease severity.The NanoSuit method is a biomimetic technique inspired by the ability to observe live Drosophila larvae using a field emission scanning electron microscope (FE-SEM), which requires high vacuum conditions 14,15 . The NanoSuit-CLEM (correlative light and electron microscopy) method, which applies NanoSuit technology,…”

“…The NanoSuit method is a biomimetic technique inspired by the ability to observe live Drosophila larvae using a field emission scanning electron microscope (FE-SEM), which requires high vacuum conditions 14,15 . The NanoSuit-CLEM (correlative light and electron microscopy) method, which applies NanoSuit technology,…”