Microscopic colitis and its associations with complications observed in classic inflammatory bowel disease: a systematic review

Solberg, Felix; Ohlsson, Bodil

doi:10.1080/00365521.2020.1739325

Cited by 8 publications

(7 citation statements)

References 36 publications

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“…Los criterios actuales para el diagnóstico de estas dos entidades son los descritos en la clasificación de Roma IV, y se diferencian entre sí por el dolor abdominal que generalmente está ausente en la DF demostrado en otros estudios (12) . También se ha relacionado con el antígeno leucocitario humano DQ2, el cual se asocia con otras enfermedades autoinmunes y con alteraciones del microbioma fecal (disminución de la bacteria Akkermansia muciniphila) (10) .…”

Section: Discussionunclassified

“…Muchos autores incluyen actualmente a la CM dentro del grupo de la EII, al lado de patologías tan importantes como la EC o la colitis ulcerativa (CU), aunque presenta características muy disímiles en cuanto a la edad, síntomas, evolución de la enfermedad y tratamiento. La EC y la CU a menudo se consideran enfermedades sistémicas, que además de afectar la región colorrectal se asocian frecuentemente con otras enfermedades y con complicaciones de tipo neoplásico, las cuales no se han podido demostrar en relación con la CM (10) .…”

Section: Diagnósticounclassified

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Colitis microscópica, serie de casos y revisión de la literatura

Ortíz

Rendón-Hernández

Ballén-Párraga

2022

Rev. colomb. Gastroenterol.

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Introducción: la colitis microscópica es una enfermedad benigna y multifactorial caracterizada por la presencia de diarrea acuosa y alteraciones histológicas en la mucosa colónica. La incidencia de esta enfermedad viene en aumento y su diagnóstico se realiza cada vez con mayor frecuencia. Métodos: estudio retrospectivo en el que se revisaron los pacientes por medio de colonoscopia y biopsias por diagnóstico de diarrea crónica en un período de 22 meses en una unidad de gastroenterología, y en quienes mediante la clínica y el análisis histológico se confirmó el diagnóstico de colitis microscópica. Resultados: en el período de estudio se realizó un total de 2849 colonoscopias, 116 en pacientes con diarrea crónica. Se identificaron 15 pacientes con colitis microscópica, 12 fueron hombres (80 %) y solo hubo 3 mayores de 60 años (20 %). Conclusión: a diferencia de lo informado en la literatura mundial, en este estudio se encontró que la colitis microscópica en nuestros pacientes compromete especialmente al sexo masculino (relación hombre/mujer: 4/1) y se presenta en personas jóvenes, con un promedio de edad de 47,5 años (rango de 21 a 82 años).

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Section: Discussionunclassified

Section: Diagnósticounclassified

Colitis microscópica, serie de casos y revisión de la literatura

Ortíz

Rendón-Hernández

Ballén-Párraga

2022

Rev. colomb. Gastroenterol.

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“…MC is a clinicopathologic disorder, histologically subdivided into LC with increased intraepithelial lymphocytes (>20/100 colonic surface epithelial cells) and CC with atypically thickened subepithelial collagen band >10 μm [4]. MC is postulated to develop via an immunological response to various mucosal insults in predisposed patients [3].…”

Section: Discussionmentioning

confidence: 99%

“…IBD has known complications such as malignancy and immune-mediated diseases such as ankylosing spondylitis and autoimmune thyroid disease. A systematic review showed an association between rheumatic diseases and MC [4,5], but no real conclusions can be made regarding MC and its association with classic IBD complications [4]. The complication rates and prognosis with MC-IBD overlap are unknown.…”

Section: Discussionmentioning

confidence: 99%

3155 Macroscopic to Microscopic: A Case of Crohn's Disease Progressing to Collagenous Colitis

et al. 2019

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The association between microscopic colitis (MC) and inflammatory bowel disease (IBD) is uncertain and infrequently reported. Rare cases in the literature consist of simultaneous MC and IBD, or progression of one condition to the other. We present a unique case of clinically and endoscopically diagnosed and successfully treated IBD that revealed MC on histology months later due to reappearance of diarrhea. Common pathophysiologic mechanisms, such as tumor necrosis factor α and T helper type 1 cells, may explain the MC and IBD relationship. During endoscopy, a prompt biopsy should be taken if suspicious for MC, thus decreasing the duration of patient's symptoms and saving healthcare costs.

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“…Smoking and some drugs are associated with the disease, although the causal mechanism cannot be proved. Complications commonly associated with Crohn's disease or ulcerative colitis; for example, malignancy and liver diseases, are not associated with MC 7 . Thus, the pathophysiology in MC should differ from the pathophysiology in classic inflammatory bowel disease.…”

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confidence: 99%

New European statements and recommendations for the management of microscopic colitis

Ohlsson

2021

UEG Journal

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New European statements and recommendations for the management of microscopic colitis Microscopic colitis (MC) is a chronic inflammatory bowel disease, divided into collagenous colitis (CC) and lymphocytic colitis (LC). The most common symptom of MC is chronic watery, non-bloody diarrhoea, but other gastrointestinal symptoms such as abdominal pain and bloating are also frequently observed. 1 The chronic watery diarrhoea leads to great inconveniences for the patient, with faecal urgency, nocturnal stools and faecal incontinence. As the disease may have vague and non-specific signs on endoscopy, histopathological diagnosis is mandatory, which is unfortunately sometimes overlooked. The clinical handling of the patient may be a challenge, because the symptoms may be refractory to conventional treatment. 2 In the current issue of the United European Gastroenterology Journal, the United European Gastroenterology and the European Microscopic Colitis Group present their statements and recommendations for the disease in the European guidelines on MC. 3 These guidelines are developed after an impressive research and assessment of published literature within the field. The systematic review was performed in accordance with the PRISMA guidelines, and the GRADE methodology was applied to assess the quality of the studies. Meta-analyses were conducted when applicable. The publication is presented as answers to the most common questions regarding epidemiology, sex differences, lifestyle habits, aetiology and pathogenesis, clinical manifestations, assessment of disease activity, diagnostic criteria and treatment options. For each question and answer, the level of evidence, the strength to budesonide, thiopurines, anti-tumour necrosis factor drugs or vedolizumab can be used in selected patients. Other drugs, such as mesalazine, bismuth subsalicylate, probiotics, corticosteroids and methotrexate, are not recommended.

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Microscopic colitis and its associations with complications observed in classic inflammatory bowel disease: a systematic review

Cited by 8 publications

References 36 publications

Colitis microscópica, serie de casos y revisión de la literatura

Colitis microscópica, serie de casos y revisión de la literatura

3155 Macroscopic to Microscopic: A Case of Crohn's Disease Progressing to Collagenous Colitis

New European statements and recommendations for the management of microscopic colitis

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