Microscopic and pharmacognostic standardization of <scp><i>Astragalus scorpiurus</i></scp> Bunge

Uza, Noor Ul; Dastagir, Ghulam

doi:10.1002/jemt.23907

Cited by 8 publications

(9 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…By identifying the structural properties of plant components, microscopy enables a more thorough investigation of crude drug. Uza and Dastagir (2021) emphasized the importance of anatomy in detecting adulterants and pollutants in herbal medications and providing tools for assessing the authenticity and quality control of crude pharmaceuticals. For this reason, we can say that studying the morphology and micrometry of the chosen plant parts has given us a better knowledge of the species within the same genus (Bekoe et al, 2020).…”

Section: Resultsmentioning

confidence: 99%

“…Even minute objects that are tightly spaced may be identified because of the excellent resolution. There has been a significant rise in the magnification of objects since traditional lenses were replaced with electromagnets (Uza & Dastagir, 2021). SEM's characteristics make it suitable for modern taxonomic research of plants and is used t characterize the micromorphological characteristics of herbal medications.…”

Section: Comparative Powder Drug Study Of Fruit (Sem)mentioning

confidence: 99%

“…Herbal medicines may be identified and individual components of a combination can be detected using microscopy. To optimize efficacy and reduce undesirable side effects, it is critical to assure the quality and purity of herbal medications (Uza & Dastagir, 2021).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Anatomical and histochemical characterization of some highly medicinal plants as a tool for quality control

Dastagir

Hussain

Uza

2023

Microscopy Res & Technique

Self Cite

View full text Add to dashboard Cite

Medicinal plants are richest source of chemical compounds that can be used to evolve novel drugs. According to World Health Organization (WHO), in developing countries more than 3.5 billion people relay on herbal drugs for their primary health care. In the present study, an attempt was carried out to authenticate some selected medicinal plants (Fagonia cretica L., Peganum harmala L., Tribulus terrestris L., Chrozophora tinctoria L. Raf. and Ricinus communis L.) from family Zygophyllaceae and Euphorbiaceae using light and scanning electron macroscopic techniques. Macroscopic evaluation and comparative anatomy (Light Microscopy) of the root and fruits revealed great diversity in macro and microscopic features. Scanning electron microscopy (SEM) of root powder showed non‐glandular trichomes, stellate trichomes, parenchyma cells and vessels. Fruits SEM exhibited non‐glandular trichomes, glandular trichomes, stellate trichomes, peltate trichomes and mesocarp cells. Both macroscopic and microscopic evaluation plays a crucial role in the correct substantiation and validation of novel sources. These findings can serve as an essential source of information to accomplish the authenticity and to appraise the quality and purity of the herbal drugs in accordance to WHO guidelines. These parameters can be used to distinguish the selected plants from their commonly used adulterants. Research Highlights In the current work, five plants (Fagonia cretica L., Peganum harmala L., Tribulus terrestris L., Chrozophora tinctoria L. Raf. and Ricinus communis L.) from Zygophyllaceae and Euphorbiaceae were investigated for macroscopy and microscopy (LM & SEM) for the first time. Macroscopic and microscopic evaluation disclosed great diversity in morphology and histology. Microscopy is the backbone of standardization process. Current study helped in correct identification and quality assurance of the plant materials. Their statistical investigation may possess great potency for plant taxonomists to further appraise the vegetative growth and tissue development which is requisite especially for fruit to enhance the yield of herbal drugs and their formulation. Further molecular studies, compounds isolation and characterization are required to deepen the knowledge of these herbal drugs.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Comparative Powder Drug Study Of Fruit (Sem)mentioning

confidence: 99%

See 1 more Smart Citation

Anatomical and histochemical characterization of some highly medicinal plants as a tool for quality control

Dastagir

Hussain

Uza

2023

Microscopy Res & Technique

Self Cite

View full text Add to dashboard Cite

show abstract

“…To control the quality of raw medications, the WHO has proposed a set of standards. An essential method used to obtain standardization of species products is microscopy (Rashid et al 2018;Majid et al 2021;Uza & Dastagir 2022). For the pharmacognostic standardization of medicinal plants, light microscopy is often used to describe the architecture and histochemistry of a plant (Rosa et al 2021;Abbas et al 2022;Uza & Dastagir 2022).…”

Section: Introductionmentioning

confidence: 99%

“…An essential method used to obtain standardization of species products is microscopy (Rashid et al 2018;Majid et al 2021;Uza & Dastagir 2022). For the pharmacognostic standardization of medicinal plants, light microscopy is often used to describe the architecture and histochemistry of a plant (Rosa et al 2021;Abbas et al 2022;Uza & Dastagir 2022). According to Gissi et al (2022) and Marques et al (2022), anatomy and histology are essential for identifying and resolving taxa within a complex species at the species and generic levels.…”

Section: Introductionmentioning

confidence: 99%

Morphology, anatomy, and histochemistry of three species of Jatropha: a contribution to plant recognition and selection

Syahruni,

Umar,

Todingbua

et al. 2023

Plant Biol J

View full text Add to dashboard Cite

Jatropha, a traditional medicinal plant known for its anti‐inflammatory, antimicrobial, anticancer, antiviral, antidiabetic, and anticoagulant properties, was the subject of our study. We examined the morphology and chemical composition of three Jatropha species using cross‐ and longitudinal sections of fresh samples, observed with light microscopy. Histochemical analysis was conducted using various reagents to reveal the metabolites present. Anatomically, the distinguishing feature among the three Jatropha species was the presence of secretory cavities. These structures were identified in the petiole and stem bark of J. multifida, while in J. gossypiifolia and J. curcas they were present in roots. The stem bark cells of J. gossypiifolia were roundish in shape, whereas the others were rectangular. Laticifers were detected in the leaves, petioles, and stem bark of all three Jatropha species, while idioblasts were present in almost all organs. Histochemical tests revealed that excretory idioblasts and laticifers in Jatropha species contained alkaloids, phenolics, lipophilic compounds, and terpenoids. The cuticle of non‐glandular trichomes contained terpenoids, while phenolic compounds were found within the secretory cavities. These findings contribute to the identification of Jatropha species and provide valuable insights for the selection and collection of specific plant organs containing bioactive compounds.

show abstract

Pharmacognostic standardization and machine learning–based investigations on Akebia quinata and Akebia trifoliata

Qiu

Shi

2023

Biomedical Chromatography

View full text Add to dashboard Cite

Currently, Akebiae Caulis is being used in clinical practice, but there are few reseaches on its different varieties. To ensure the accuracy and effectiveness of clinical practice, this study distinguished the Akebia quinata (Thunb.) Decne. and Akebia trifoliata (Thunb.) Koidz, using organoleptic evaluation, microscopic observation, fluorescence reaction, physicochemical properties, thin‐layer chromatography, IR spectroscopy, HPLC, four machine learning models, and in vitro antioxidant methods. Analysis of the powders of these two varieties using optical microscopy revealed the presence of starch granules, cork cells, crystal fibers, scalariform vessels, and wood fibers. Scanning electron microscopy revealed the presence of scalariform vessels, pitted vessels, wood fibers, and calcium oxalate crystals. Several tissues, including the cork layer, fiber population, cortex, phloem, pith, xylem, and ray, were found in the transverse section. In addition, thin‐layer chromatography was used to identify two components: oleanolic acid and calceolarioside B; 11 common peaks were identified in 15 batches of SAQ and 5 batches of SAT by using HPLC. Support vector machine, BP neural networks, and GA‐bp neural networks were able to predict 100% accurately of the different origins of stem of Akebia quinate (Thunb.) Decne (SAQ) and Akebia trifoliata (Thunb.) Koidz (SAT). Extreme learning machine achieved a correct rate of 87.5%. Meanwhile, Fourier‐transform infrared spectroscopy fingerprint identified nine characteristic absorption peaks of the secondary metabolites of SAQ and SAT. 2,2‐Diphenyl‐1‐1‐picrylhydrazyl experiment revealed that the IC50 values of SAQ and SAT extracts were 155.49 and 128.75 μg/ml, respectively. For the 2,2′‐azino‐bis‐(3‐ethylbenzothiazoline‐6‐sulfonic acid) assay, the IC50 value of SAT extract was found to be 269.24 μg/ml, which was lower than that of SAQ extract (IC50 = 358.99 μg/ml). This study successfully used different methods to differentiate between A. quinata (Thunb.) Decne. and A. trifoliata (Thunb.) Koidz., to help decide on which type to use for clinical application.

show abstract

Microscopic and pharmacognostic standardization of Astragalus scorpiurus Bunge

Cited by 8 publications

References 31 publications

Anatomical and histochemical characterization of some highly medicinal plants as a tool for quality control

Anatomical and histochemical characterization of some highly medicinal plants as a tool for quality control

Morphology, anatomy, and histochemistry of three species of Jatropha: a contribution to plant recognition and selection

Pharmacognostic standardization and machine learning–based investigations on Akebia quinata and Akebia trifoliata

Contact Info

Product

Resources

About