Abstract:Background: We conducted this study was to identify any difference in platelet-derived exosome micro-RNA (microRNA) profile between patients with in-stent restenosis and patients without restenosis using gene sequencing.Method: Platelet-derived exosomes(PDEs) were isolated through ultracentrifugation and validated by Western blotting, transmission electron microscope and NanoSight analysis. The platelet-derived exosome microRNA expression profile was identified by Illumina Hiseq2000/2500 sequencing, and valida… Show more
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