MicroRNAs as serum biomarker for Senecio brasiliensis poisoning in cattle

Winter, Evelyn; Cisilotto, Júlia; Goetten, André Lucio Fontana; Veiga, Angela Patricia Medeiros; Ramos, Adriano Tony; Zimermann, Francielli C; Reck, Carolina; Creczynski-Pasa, Tânia Beatriz

doi:10.1016/j.etap.2022.103906

Cited by 2 publications

(2 citation statements)

References 86 publications

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“…It is known to be one of the most common plant-related poisonings in cattle. In a study that performed miRNA profile analysis to determine potential diagnostic biomarkers for Senecio brasiliensis poisoning, it was reported that miR-122, miR-885, and especially miR-21 could be potential biomarkers with high specificity and sensitivity in the detection of poisoning (Winter et al, 2022).…”

Section: Cattlementioning

confidence: 99%

MicroRNAs as potential biomarkers in ruminant, avian and porcine

Kalaycılar,

Yardibi

2024

Journal of Istanbul Veterinary Sciences

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In recent years, studies on microRNAs have increased considerably. miRNAs are small RNA molecules, ranging from 19 to 25 nucleotides in length, that control the suppression of target genes after transcription. MiRNAs serve as fine-tuning factors that influence the expression of up to 60% of all mammalian protein-coding genes. Unlike proteins, miRNA sequences are widely conserved across species. This conservation strongly suggests that miRNAs emerged early in evolution and maintain their functional importance. It has been revealed that these small structures containing a small number of nucleotides can act as critical points in the organism. While traditional cancer biomarkers are mainly produced by tumor tissues or normal embryo tissues, they are absent or present in small amounts in tissue organs and the blood of healthy adults. MiRNAs can be easily detected in the blood, making them selectable candidates as biomarkers for disease. The ruminant family, one of the most diverse subspecies of terrestrial mammals, lives in a wide variety of environments worldwide and is known to have a major impact on various ecosystems and industries, including agriculture, daily activities, and cultures. MiRNAs have a significant impact on the physiology of farm animals, biological development, and cell differentiation. In this review, we will examine miRNAs that have been identified as candidates or potential candidates for the diagnosis and treatment of diseases seen in ruminants, pigs, and avians in recent years. In this way, we will provide a perspective to prevent diseases that can cause great economic losses in veterinary medicine and the production industry.

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Section: Cattlementioning

confidence: 99%

MicroRNAs as potential biomarkers in ruminant, avian and porcine

Kalaycılar,

Yardibi

2024

Journal of Istanbul Veterinary Sciences

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“…and Solanum spp. are plant genera widely known in South America for their weedy characteristics, especially in southern Brazil and Uruguay [1,2]. Particularly, Senecio brasiliensis Less., also known as "maria-mole" and "maçanilha", is a weed belonging to the Asteraceae family found in a variety of habitats including pastures and roadsides [3].…”

Section: Introductionmentioning

confidence: 99%

Extracts of Senecio brasiliensis and Solanum viarum as Potential Antifungal and Bioherbicidal Agents

Confortin,

Todero,

Luft

et al. 2024

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Ultrasound-assisted extraction is an interesting tool for obtaining bioactive compounds from plant matrices applicable as agricultural bio-inputs, as it increases the extraction efficiency, reducing the process time and the use of solvents. This technique uses ultrasonic waves to break down plant cell walls, releasing bioactive compounds quickly and effectively and promoting a sustainable path to obtaining bio-inputs. Accordingly, this research study reports pioneering results regarding the herbicidal and fungicidal potential of different extracts obtained from Senecio brasiliensis (samples from flowers, leaves, and stalks) and Solanum viarum (samples from fruits and roots), two weeds typically found in rural areas of South America. The fungicidal activity of the samples was tested on two fungi, i.e., Fusarium graminearum and Sclerotinia sclerotiorum, while the herbicidal action of the extracts was evaluated in pre-emergence tests in cucumber (Cucumis sativus) seeds. The successful results indicated a high antifungal and herbicidal potential of the extracts obtained for both weeds, with the inhibitory effect against both fungi achieving up to 82%, and the inhibition of C. sativus seed germination reaching 100% for all samples.

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MicroRNAs as serum biomarker for Senecio brasiliensis poisoning in cattle

Cited by 2 publications

References 86 publications

MicroRNAs as potential biomarkers in ruminant, avian and porcine

MicroRNAs as potential biomarkers in ruminant, avian and porcine

Extracts of Senecio brasiliensis and Solanum viarum as Potential Antifungal and Bioherbicidal Agents

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