MicroRNA expression profiling of urine exosomes in children with congenital cytomegalovirus infection
Yuka Torii,
Takako Suzuki,
Yuto Fukuda
et al.
Abstract:Congenital cytomegalovirus (cCMV) infection can damage the central nervous system in infants; however, its prognosis cannot be predicted from clinical evaluations at the time of birth. Urinary exosomes can be used to analyze neuronal damage in neuronal diseases. To investigate the extent of neuronal damage in patients with cCMV, exosomal miRNA expression in the urine was investigated in cCMV-infected infants and controls. Microarray analysis of miRNA was performed in a cohort of 30 infants, including 11 sympto… Show more
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