MicroRNA-877-5p promotes osteoblast differentiation by targeting EIF4G2 expression
YingChao Shen,
Yang Zhang,
Qiang Wang
et al.
Abstract:Stimulating bone formation potentially suggests therapeutics for orthopedic diseases including osteoporosis and osteoarthritis. Osteoblasts are key to bone remodeling because they act as the only bone-forming cells. miR-877-5p has a chondrocyte-improving function in osteoarthritis, but its effect on osteoblast differentiation is unknown. Here, miR-877-5p-mediated osteoblast differentiation was studied. Real-time reverse transcriptase-polymerase chain reaction was performed to measure miR-877-5p expression duri… Show more
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